MSK Flashcards
Which % FRAX score indicates DEXA scan
10%
XR findings for ankylosing spondylitis
Subchondral erosions (loss of joint space also seen in eg OA
Sclerosis (higher density)
Squaring of lumbar vertebrae
1st line Mx for ankylosing spondylitis
Exercise e.g. swimming
NSAIDs
Which nerve innervates foot dorsiflexion and sensation of dorsum
L5
Which nerves control the leg reflexes
Knee jerk = L3 and L4
‘Three four kick the door’
Ankle jerk = S1 and S2
‘One two buckle my shoe’
Which Abx not to take with methotrexate
TriMETHoprim
Which t2dm medication increases fracture risk
Glitazones e.g. pioglitazone.
Most common cardiac manifestation of SLE
Pericarditis
Also presents with fatigue , fever, mouth ulcers, lymphadenopathy, skin rashes, photosensitivity, arthralgia, pleurisy its crazy
4 key XR changes in osteo
LOSS
Loss of joint space
Osteophytes (bone spurs)
Subarticular sclerosis (increased density along the joint line)
Subchondral cysts (fluid filled holes in the bones)
Boutonniere’s vsswan neck deformity
Boutonnières is flexed PIP and hyperextended DIP
Swan neck is hyperextended PIP and flexed DIP
Both in RA
2 common SE of sulfasalazine
Orange urine
Male infertility (reduces sperm count)
3 common SE of hydroxychloroquine
Retinal toxicity (e.g. uveitis)
Blue-grey skin pigmentation
Hair bleaching
Skin presentation of SLE
Malar rash worsened by sunlight
Which antibody is most specific to SLE
Anti-dsDNA (double stranded)
Antiphospholipid syndrome can then occur in people with SLE causing increased risk of VTE
5 complications of SLE
Recurrent miscarriages
Pericarditis
CVD and hypertension due to chronic inflam in BVs
Pleuritis/ ILD
Anaemia
Nephritis
VTE
Neuropsychiatric (optic neuritis/ psychosis)
How does limited cutaneous systemic sclerosis present
CREST
Calcinosis- calcium deposits on e.g. fingertips
Raynaud’s
Esophageal dysmotility- swallowing, reflux, pain
Sclerodactyly- skin tightening of hands
Telangiectasia- dilated bv in skin
How does diffuse cutaneous systemic sclerosis differ from limited
CREST Sx in limited
Plus:
- CV problems e.g. hypertension and CAD
- lung problems e.g. pulmonary fibrosis
- kidney problems e.g. scleroderma renal crisis
Which management for diffuse cutaneous systemic sclerosis do you need to be careful doing
Steroids can cause scleroderma renal crisis which is a complication of DCSS
Which blood test for myositis
CK really high
What do you give in antiphospholipid syndrome to prevent complications
Long term warfarin - target 2-3
Give LMWH and aspirin in pregnancy
Prevents DVTS and miscarriages etc
Which test to diagnose Sjögrens
Schirmer test
Filter paper under lower eyelid- moisture should travel 15mm, less than 10 is significant