MS - management and interventions

Question 1

Medical Management in MS: Implications for Rehab

Answer 1

Earlier diagnosis

Earlier treatment

Decreased lesion load/sites

More effective rehab

Question 2

Medical management of MS

Answer 2

Immunomodulators

Steroids

Question 3

What does CRAB stand for?

Answer 3

Copaxone
Rebif
Avonex
Betaseron

Question 4

What do immunomodulators do?

Answer 4

Copaxone (glatiramer acetate)
Rebif (interferon beta 1a)
Avonex (interferon beta 1a)
Betaseron (interferon beta 1b)
Has been shown to be effective in decreasing the frequency and severity of relapsing-remitting MS
Flu-like symptoms are a frequent side-effect
Less effective in chronic progressive MS

Question 5

Methotrexate is a type of and is used for

Answer 5

Immunomodulators

For SP-MS; suppresses the immune system

Question 6

Mitoxantrone is a type of and is used for

Answer 6

Immunomodulators

For worsening of RR, PR, SP-MS

Question 7

Corticosteroids and MS

Answer 7

High Dose Intravenous Methylprednisolone
Often treatment of choice for acute exacerbations
Limits inflammatory response
Reduces tissue edema
Restoration of the BBB
Immunomodulation

Question 8

Methylprednisolone is a type of and is used for

Answer 8

Corticosteroids

High Dose Intravenous Methylprednisolone

Often treatment of choice for acute exacerbations

• Limits inflammatory response
• Reduces tissue edema
• Restoration of the BBB
• Immunomodulation