MS Endocrine Flashcards
Usual COD of Diabetes Insipidus (2)
Dehydration & Hypovolemic Shock (Vascular)
☆ Leading cause of SIADH
Adenoma in hypothalamus or PPG
Usual COD of SIADH (2)
Seizures & Arrhythmia
WOF in SIADH
Dilutional Hyponatremia
This can cause arrhythmia (brady / AV block) and seizures
DOC for DI
Lifetime HRT of ADH (-pressin)
Emergency: IV, IM
Maintenance: Intranasal / Oral
DOC for SIADH
Demeclocyline
- decreases ADH production
Drug used for DI which stimulates ADH release (neuro) and lowers resistance to ADH (nephro)
Chlorpropramide (Diabenase)
Type of diuretics preferred in SIADH
Loop Diuretics
(Decreased K = Increased Na)
Leading cause of hypoparathyroidism
Autoimmune
Leading cause of hyperparathyroidism
Adenoma in PTG
WOF in Hypoparathyroidism
Laryngospasm & Bronchospasm
DOC for Hypoparathyroidism
HRT of PTH for Life
DOC for hyperparathyroidism
Calcitonin
☆ Drug for hypoparathyroidism
Aluminum Hydroxide (Amphogel)
- Form of antacid; a phosphate binder. Excessive phosphorus in blood is delivered to stool to be excreted.
Decreased PHO = Increased Ca
Hormone responsible for withdrawal of calcium to bone
Parathyroid Hormone / Parat Hormone
Hormone responsible for depositing calcium in blood to bone
Thyrocalcitonin
Leading cause of primary hypothyroidism
Autoimmune
Hashimoto / Autoimmune Thyroiditis
☆ Leading cause of primary hyperthyroidism
Autoimmune Irritation
Earliest sign of hypothyroidism
Fatigue / Weakness / Body Malaise
Earliest Sx of Hyperthyroidism
Shakiness / tremors starting at the hands
WOF in Hyperthyroidism
Risk for Airway Obstruction (Goiter)
Dalyrymple’s Sign (Thyroid Stare)
- red eyes, infrequent blinking
Von Graefe’s Sign (Lid-Lag Sign)
☆ WOF in Hypothyroidism
Myxedema Coma
☆ WOF in Hyperthyroidism
Thyrotoxic Crisis (Thyroid Storm)
Early sign of thyrotoxic crisis
Constant elevation of HR and temperature
Best Dx Test for Hypo and hyperthyroidism
Needle Biopsy (FNA)
☆ RAIU / Thyroid Scan ☆
In RAIU, what is given to check?
Low Dose of Sodium Iodide 123
Sodium 131 = Treatment = High Dose
Type of antihypertensive drugs to be used for hyperthyroidism
Beta Blocker & DiVe of CCB
(-) Chromo, Dromo, Ino
Contraindicated antipyretic for hyperthyroidism
Salicylate based because it has the ability to increase T3 and T4
☆ Solution used for hyperthyroidism
Lugol’s Solution (Saturated Potassium Iodine / SSKI)
- Decreases size and vasculrity of thyroid
- Use STRAW to prevent deep staining
☆ DOC for hyperthyroidism
Tapazole, Methimazole, PTU (Most Potent)
A/E of PTU (Prophylthiouracil)
Agranulocytosis / Blood Dycrasia
WOF: Sore Throat + Fever
☆ WOF: Thyroidectomy Post-Op Complications ☆
- Airway Obstruction (Bedsite ET)
- Bleeding / Hemorrhage
- Hypocalcemia (Calcium Gluconate at Bedside)
- Laryngeal Nerve Damage (Hoarseness of voice is normal for 1-6 weeks; no voice when speaking is abnormal) ☆
- Thyroid Storm
Straw Drugs
LITT
- Lugol’s
- Iron
- Tetracycline
- Thorazine / Chlorpromazine