MS Assessment Flashcards
What do Myelin Sheaths deteriorate to?
Sclerotic Plaques
(Hardened scars or plaques)
How does the deterioration of Myelin Sheaths affect Action Potentials and Control of Muscle?
Slower and creates an impairment of control for skeletal and smooth muscle
Sclerotic Plaques lead to…
Weakness, Spasticity, Sensory Loss in Balance, Gait, and Functional Activities
Neurons require Energy Metabolism
Oxidative process
What is associated with MS?
Mitochondrial Genetic Variants
Deficient Mitochondrial Metabolism
Can generate more Reactive Oxygen species (ROS) that can wreak havoc in the cell
Key Factors in the induction of demyelination and neurodegeneration
Mitochondrial injury and subsequent energy failure
Mitochondrial Dysfunction in the MS
Respiratory Chain Deficiency
Abnormal Mitochondrial Transport
Abnormal Mitochondrial Gene Expression
Oxidative Damage
Impiarment Energy Production
Exercise on Neurodegenerative Diseases
Contributes to metabolic and mitochondiral reprogramming of tissues via temperature, hypoxia, BP, or pH
Sensory Axons involved in MS
MS is a Sensory-Motor Condition, C-Fibers are not injured and pain is unaltered
Intervention Framework for Posture and Gait Control
Sensory Feedback
Neural Command
Motor Output
Movement Generated
Muscular Performance in MS
Synergistic Patterns
Ataxia Coordination
Flaccid/Weakness
Selective Strength
Speed/Accuracy
Tone in MS
Hypertonicity
DTR
Spasticity
Spasms
Cranial Nerves in MS
CN II, III, IV, and VI
CN VIII
CN IX
CN V
CN VII
Sensory in MS
Proprioception
Somatosensory
Visual Perceptual
Vibrations
CN II Examination
Visual Field loss / Blurred Vision
Presenting symptom of disease
CN III and VI Examination
Abnormality of Horizontal Gaze
Saccades
CN V Examination
Most common facial numbness
CN VIII Examination
Vertigo
Proprioception is gathered from…
Mainly the Muscle Spindle (Length and Velocity) and the GTO (Force Production or Tension)
Conscious knowledge of Movement goes through the…
Dorsal Column Pathway
Proprioception and Vibration
Unconsvious proprioception to the Cerebellum is from…
The muscle spindles and GTO
MS involves which Pathways
Dorsal Column (Conscious)
AND
Muscle Spindles nad GTO (Unconscious)
Weakness in MS
From spinal cord plaques and cortical plaques
Isometric, dynamic strength, and power are all impaired more often in the LE
UE is coordination
