MRCS May 4/52 Flashcards

1
Q

what nerve roots contribute to radial nerve

A

C5 to T1

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2
Q

which cell phase does RNA synthesis occur in

A

G1 and G2

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3
Q

what happens in G0 phase of cell cycle

A

resting phase

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4
Q

what phase does p53 halt cell progress?

A

p53 halts cells from going into S phase

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5
Q

what neurotransmitter is secreted carcinoid cells

A

serotonin

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6
Q

what is the diagnostic test for carcinoid syndrome

A

raised levels of urinary 5-HIAA (metabolite of serotonin)

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7
Q

which muscle splits to form anterior and posterior rectus sheath?

A

internal oblique

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8
Q

what is kocher’s incision

A

3cm away and parallel from costal margin, ideal for cholecystectomy

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9
Q

what layers are gone thru in a kocher’s incision

A
skin, subcut fat, scarpas fascia
medially: ant. rectus sheath, rectus abdominis, post. rectus sheath. 
laterally : EO IO TA
transversalis fascia
preperitoneal fat
peritoneum
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10
Q

layers traversed in a midline laparotomy incision?

A

skin, subcut fat, scarpa’s fascia
linea alba
trasversalis fascia, preperitoneal fat, peritoneum

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11
Q

surface marking for gallbladder?

A

at the intersection of linea semilunaris and the costal margin at the 9th costal cartilage

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12
Q

what incision used for gastric surgery

A

double kocher (rooftop) incision

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13
Q

what is gridiron’s incision, what is it used for, how to incise,

A

aka mcburney’s incision, used for appendicectomy, at mcburney’s point, 90deg to line from asis to umbilicus .

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14
Q

what to watch out for in using gridiron’s incision

A

iliohypogastric, ilioinguinal nerve and deep circumflex artery

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15
Q

what is the course of iliohypogastric and ilioinguinal nerve

A

exit their nerve roots and travel laterally along iliac crest, along inguinal ligament and into the pubic region

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16
Q

what kind of groin hernia is more common in children

17
Q

in who are direct inguinal hernias more common

A

male adults

18
Q

what is the order of commonness of groin hernia in adult females

A

indirect > femoral > direct

19
Q

difference between midinguinal point and midpoint of inguinal ligament

A

midpoint of inguinal ligament = midpoint of ASIS and pubic tubercle, deep inguinal ring found here

midinguinal point is midway from ASIS to pubic symphysis; femoral artery lies here

20
Q

what is the attachments of the lateral and medial crus of superficial inguinal ring? what forms the base of the superficial inguinal ring

A

laterally - pubic tubercle
medially - pubic crest
floor = pubic crest

21
Q

what is at the medial boundary of the deep inguinal ring

A

inf. epigastric artery

22
Q

what forms the spermatic cord?

A

internal spermatic fascia - transversalis fascia
cremasteric fascia - internal oblique + transversus abdominis
external spermatic fascia - external oblique

23
Q

contents of inguinal canal in male

A

3 arteries - testicular, vas, cremasteric
3 nerves - testicular, genital branch of genitofemoral, iliinguinal
3 veins - testicular, cremasteric, pampiniform plexus
lymph drainage to para-aortic nodes

24
Q

what forms ceiling of inguinal canal

A

laterally formed by transversus abdominis, joined by internal oblique to form conjoint tendon at medial end, arches over to strength posterior wall behind superficial ring

25
what forms anterior wall of inguinal canal
external oblique mostly, strengthened lateraly by internal oblique
26
what forms posterior wall of inguinal canal
mostly transversalis fascia, strengthened medially by conjoint tendon
27
Indications for surgical repair of popliteal aneurysm
Symptomatic - claudication, pain, limb ischaemia | Asymptomatic - thrombus (risk of embolisation)
28
Deficit in which factor causes christmas disease? What is it AKA?
Factor 9 - aka haemophilia B
29
Between UC and crohns, which is more likely to have gallstones and kidney stones
Crohns
30
Def in which electrolyte can cause impaired parathyroid hormone secretion?
Hypomagnesaemia
31
What lvl is the origin of hepatic portal vein found at
Transpyloric plane - L1
32
Most common malignant testicular malignancy?
Seminoma - 40%
33
What tumor marker is used in seminoma?
BHCG
34
What tumor marker is used in teratoma?
AFP
35
MOA of ketoconazole?
Inhibits biosynthesis of ergosterol
36
MOA of nystatin and amphotericin B
Interacts with membrane ergosterol to affect membrane permeability
37
What heart issues is associated with carcinoid syndrome
Right heart valve lesions - TR, TS, PS
38
Why is a pyllodes breast tumor?
Fast growing stromal cell tumour in breast, 50% benign
39
What bloods will be abnormal in compartment syndrome?
high ck, high K, high P, high uric acid, metabolic acidosis