MRCPsych Paper B - Critical review Flashcards
Type of randomization - using odd/even numbers of DOB
Quasi-randomization
*because it is not reproducible
Type of randomization - coin toss
not randomization
Type of randomization - computer generated random list
Simple randomization
Type of randomization - blocks of 6
Block randomization
Type of randomization - randomize clusters or catchment zones, not individuals
Cluster randomization
Type of randomization - next allocation is based on the characteristics of what is already present
Minimisation
How to control confounders?
Restriction
Matching
Randomisation
Stratification
Multivariate analysis
Type of bias - difference between hospital/admitted population and community population
Berkson bias
Type of bias - using incidence rather than prevalence in determining causation computations
Neyman bias
Type of bias - exclusion of comorbidities in a non-representative sample
Diagnostic purity bias
How to control measurement bias?
Blinding
How to control analysis bias?
Intention to treat analysis
Statistical study to quantify heterogeneity
Chi-square - Cochran’s Q(uantify)
*Q(uantify)
Statistical study to differentiate between heterogeneity and chance
I2 statistic
Economic study - used to decide how to spend the allocated money effectively
Cost benefit
Economic study - used to compare just the costs
Cost minimisation
Economic study - used when both interventions result in an outcome that can be measure using the same clinical scale
Cost effectiveness
Economic study - used when considering the holistic effect of what is being measured (DALY, QOL, life utility units)
Cost utility
Economic study - used when different interventions AND different outcomes are being measured using natural units
Cost consequences