Movement disorders Flashcards
1
Q
Parkinson disease- Eti
A
- 45-70 yrs onset
- 13.4/100,000
- Rural > urban
2
Q
Parkinson disease- Sx
A
TRAP:
- Tremor- resting, pill rolling, unilateral
- Rigidity- Cogwheeling, uncoordinated smooth movements. Tremor +
- Akinesia & bradykinesia- can’t initiate movements- walking, handwriting, swalloing, hypophonia
- Postural instability- shuffling gait, end block turning, unable to catch falls
- Associated: orthostasis, constipation, autonomic disfunction, anosmia
3
Q
Parkinson disease- Dx
A
- Clinical, with positive response to L-dopa
- Rule out other causes
4
Q
Parkinson disease- Tx
A
- Dopamine- L-dopa/ carbidopa
- Anticholinergics for tremor
- Tx other manifestations
5
Q
Tourette syndrome- Eti
A
- Inherited neuropsych disorder
- Onset 1 motor, at least 1 verbal
6
Q
Tourette syndrome- sx
A
- Sensory, verbal and motor tics
- Unable to control
7
Q
Myoclonus- Sx
A
- Sudden, brief, shock-like movements
- Abrupt muscle contration
- Focal, multi-focal, diffuse
8
Q
Myoclonus- Eti
A
- Cerebral anoxia (following cardiac infarction)
- Drugs and alcohol
- Levodopa tx
- Metabolic dysfunction (hepatic)
9
Q
Benign essential tremor- Eti
A
- Most common movement disorder
- > 40
- Age and family hx
10
Q
Benign essential tremor- Sx
A
- Postural kinetic tremor
- Arms, head and voice
- Unusual in legs, lips or chin
- Slow progression
- Worsens with anxiety, stress, caffeine
- Reduced by alcohol
11
Q
Benign essential tremor- Dx
A
Clinical
12
Q
Benign essential tremor- Tx
A
- Symptomatic
- Stress reduction, caffeine avoidance
- Propranolol, gabapentin
13
Q
Restless legs syndrome- Eti
A
- Idiopathic, anemia, parkinsons, pregnancy
14
Q
Restless legs syndrome- Sx
A
- Restlessness
- Curious sensory disturbances
- Irresistible urge to move limbs at periods of rest
- Disturbed nocturnal sleep and excessive daytime somnolence
15
Q
Restless legs syndrome- Tx
A
Dopamine agonosts- pramipexole
