Brain tumors Flashcards
1
Q
Metastatic intracranial tumor- Eti
A
- Most common brain tumor in adults
- To brain via blood, originating elsewhere in body
- 20% of METS go to brain
- 4-10x more common than primary brain tumor
- Lung cancer!
- Melanoma, renal cell, breast and colorectal too
2
Q
Metastatic intracranial tumor- Tx
A
- Surgery
- Chemo to original CA
3
Q
Metastatic intracranial tumor- Sx
A
- Multiple lesions on MRI
- Intracranial pressure
- Obstructive hydrocephalus
4
Q
Acoustic neuroma- Eti
A
- Nerve sheet tumor, arise from Schwann cells
- Glia of PNS
- Vestibular branch of CN VIII
- 50 yrs old
- Incidence increasing
- Tinnitus, unilateral
- Due to exposure of loud noise
5
Q
Meningioma- Eti
A
- Most common primary brain tumor
- Tumor attached to dura mater
- W>M, hx of radiation
- Slow growing
6
Q
Astrocytoma- Eti
A
- Glial cell origin, glioma
- Low grade- Stage 1-2
- High grade- Stage 3-4
7
Q
Glioblastoma- Eti
A
- Most common primary malignant brain tumor
- Cerebral white matter
- Onset > 60
8
Q
Glioblastoma- Sx
A
- Ring of tissue around necrotic core
- Spreads rapidly
- HA sudden onset- intracranial pressure, drowsiness
- Focal neuro
- Necrosis with vascular proliferation
9
Q
Meningiomas- Sx
A
Vary by location
- Visual complications of optic nerve tract
- Seizures
- Hearing loss
- Mental status change
- Weak extremities
- Obstructive hydrocephalus
- Spontaneous hemorrhage
10
Q
Acoustic neuroma- Sx
A
- Unilateral, sensorineural hearing loss
- +/- focal cranial nerve deficits
- Idiopathic longlasting tinnitus
- Sudden, unilateral hearing loss
11
Q
Acoustic neuroma- Dx
A
- MRI or CT
- Confirm loss with audiometery
12
Q
Acoustic neuroma- Tx
A
- Surgery, radiation and observation
13
Q
Astrocytoma- Well differentiated- Sx
A
- Focal or generalized seizure
- Slowly growing
- Childhood or early adulthood most common
- Anywhere in brain and spinal cord
14
Q
Astrocytoma- Dx
A
MRI or CT
15
Q
Astrocytoma-Tx
A
Surg, radiation, chemo
16
Q
Astrocytoma- Prog
A
Grade II- 7 yrs
Grade III- 3 yrs
3% 5 year survival rate
17
Q
Meningioma- Dx
A
- Round on imaging
18
Q
Meningioma- Tx
A
Surgery
19
Q
Meningioma- Prog
A
Slow growing
20
Q
Glioblastoma- Dx
A
MRI: Necrosis with vascular proliferation
- Ring of tissue around necrotic core
21
Q
Glioblastoma- Tx
A
- Excision
- Palliation
- Clinical trials
22
Q
Glioblastoma- Prog
A
Untx- double in size in 14 days
- 3% 5 yr survival
