Brain tumors Flashcards

1
Q

Metastatic intracranial tumor- Eti

A
  • Most common brain tumor in adults
  • To brain via blood, originating elsewhere in body
  • 20% of METS go to brain
  • 4-10x more common than primary brain tumor
  • Lung cancer!
  • Melanoma, renal cell, breast and colorectal too
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Metastatic intracranial tumor- Tx

A
  • Surgery

- Chemo to original CA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Metastatic intracranial tumor- Sx

A
  • Multiple lesions on MRI
  • Intracranial pressure
  • Obstructive hydrocephalus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Acoustic neuroma- Eti

A
  • Nerve sheet tumor, arise from Schwann cells
  • Glia of PNS
  • Vestibular branch of CN VIII
  • 50 yrs old
  • Incidence increasing
  • Tinnitus, unilateral
  • Due to exposure of loud noise
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Meningioma- Eti

A
  • Most common primary brain tumor
  • Tumor attached to dura mater
  • W>M, hx of radiation
  • Slow growing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Astrocytoma- Eti

A
  • Glial cell origin, glioma
  • Low grade- Stage 1-2
  • High grade- Stage 3-4
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Glioblastoma- Eti

A
  • Most common primary malignant brain tumor
  • Cerebral white matter
  • Onset > 60
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Glioblastoma- Sx

A
  • Ring of tissue around necrotic core
  • Spreads rapidly
  • HA sudden onset- intracranial pressure, drowsiness
  • Focal neuro
  • Necrosis with vascular proliferation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Meningiomas- Sx

A

Vary by location

  • Visual complications of optic nerve tract
  • Seizures
  • Hearing loss
  • Mental status change
  • Weak extremities
  • Obstructive hydrocephalus
  • Spontaneous hemorrhage
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Acoustic neuroma- Sx

A
  • Unilateral, sensorineural hearing loss
  • +/- focal cranial nerve deficits
  • Idiopathic longlasting tinnitus
  • Sudden, unilateral hearing loss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Acoustic neuroma- Dx

A
  • MRI or CT

- Confirm loss with audiometery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Acoustic neuroma- Tx

A
  • Surgery, radiation and observation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Astrocytoma- Well differentiated- Sx

A
  • Focal or generalized seizure
  • Slowly growing
  • Childhood or early adulthood most common
  • Anywhere in brain and spinal cord
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Astrocytoma- Dx

A

MRI or CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Astrocytoma-Tx

A

Surg, radiation, chemo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Astrocytoma- Prog

A

Grade II- 7 yrs
Grade III- 3 yrs
3% 5 year survival rate

17
Q

Meningioma- Dx

A
  • Round on imaging
18
Q

Meningioma- Tx

A

Surgery

19
Q

Meningioma- Prog

A

Slow growing

20
Q

Glioblastoma- Dx

A

MRI: Necrosis with vascular proliferation

- Ring of tissue around necrotic core

21
Q

Glioblastoma- Tx

A
  • Excision
  • Palliation
  • Clinical trials
22
Q

Glioblastoma- Prog

A

Untx- double in size in 14 days

- 3% 5 yr survival