*MOVED*Advanced H.M.E.N Flashcards
Which of the following conditions appears to share pathologic, clinical and radiologic features with Hand-Schuller-Christian disease, although it is uncommon disease process and the average patient is much older? A. Rosai-Dorfman disease B. Erdheim-Chester disease C. Burkitt’s lymphoma D. Malignant histiocytosis
B. Erdheim-Chester disease
Flattening and sclerosis of the 3rd metatarsal head, with enlargement and irregularity of the base of the phalanx, is an osteonecrosis most commonly seen in A.`Adolescent males B. Adult males C. Adolescent females D. Adult females
C. Adolescent females
Which of the following is common finding in children with thalassemia major? A. H-vertebraeB. Irregular vertical striations near the ends of the the long bones C. Multiple rib fractures D. Premature fusion of the epiphyses
D. Premature fusion of the epiphyses
What is the most common skeletal abnormality of hypoparathyroidism? A. Dense metaphyseal bands B. Osteoporosis C. Subcutaneous calcification D. Osteosclerosis
D. Osteosclerosis
Which bones are most commonly affected by osteomyelitis in sickle cell anemia? A. Facial bones B. Skull C. Long bones D. Vertebrae
C. Long bones
In addition to periostitis, what other radiographic findings are most often seen with chronic venous insufficiency? A. Soft tissue edema and ossification B. Lymphedema C. Osteoncrosis D. Osteomyelitis
A. Soft tissue edema and ossification
In acromegaly, what radiographic appearance may be created by the formation and approximation of osseous excrescences and enlargement of distal tufts and bases of the distal phalanges? A. Spade-like distal tufts B. Pseudoforamina C. Turret exostoses D. Bizarre parosteal osteochondromatous proliferation
B. Pseudoforamina
In myelofibrosis, fibrotic replacement of bone marrow is demonstrated by which of the following changes in signal intensity on standard spin echo magnetic resonance sequences? A. Increased T1 and decreased T2-weighted signal B. Decreased T1 and increased T2-weighted signal C. Increased T1 and T2-weighted signal D. Decreased T1 and T2-weighted signal
D. Decreased T1 and T2-weighted signal
Which of the following complications is surprisingly uncommon in Cushing’s disease? A. Vertebral compression fractures B. Renal calculi C. Osteonecrosis D. Excessive callus formation
C. Osteonecrosis
Parathyroid hormone may have a direct effect on collagen or promote its enzymatic degradation, thus predisposing patients to capsular laxity and ligamentous instability. Which of the joints below are particularly vulnerable to this? A. PIP and DIP joints B. Glenohumeral joint C. Subtalar joint D. Acromioclavicular and sacroiliac joints
D. Acromioclavicular and sacroiliac joints
The “Salt and pepper skull” of hyperparathyroidsm is due to what pathologic process? A. Intracotical bone resorption B. Diploic bone resorption C. Bone marrow hyperplasia D. Trabecular bone resorption
D. Trabecular bone resorption
What is the pathologic basis of pseudohypoparathyroidism? A. Deficient secretion of parathyroid hormone B. Surgical removal of the parathyroid glands C. The presence of biologically ineffective parathyroid hormone D. Inability of end organs to respond to parathyroid hormone
D. Inability of end organs to respond to parathyroid hormone
Which disorder is described by the following paragraph: “osteolysis of the terminal phalanges of the hands with band-like radiolucencies across the waist of one or more terminal phalanges and tuftal resorption; affecting the thumb more frequently than other digits”. A. post-traumatic acro-osteolysis B. Leprosy C. Multicentric reticulohistiocytosis D. Acro-osteolysis due to polyvinyl chloride toxicity
D. Acro-osteolysis due to polyvinyl chloride toxicity
Which facial bone is commonly involved in marrow hyperplasia in sickle cell anemia? A. Maxilla B. Mandible C. Occiput D. Zygoma
B. Mandible
The Erlenmeyer-flask deformity may be seen, among others, in Gaucher’s disease, Pyle’s disease, osteopetrosis, and which of the following: A. Hypophosphatasia B. Plumism C. Vitamin E toxicity D. Bismuth toxicity
B. Plumbism
Which of the following describes a hemolytic anemia with onset in late childhood or adolescence, featuring anemia, jaundice, and splenomegaly; with normal hemoglobin, but abnormal (inflexible) erythrocytes which get stuck in and are destroyed by the spleen? A. Aplastic anemia B. Fanconi’s anemia C. Sickle cell anemia D. Hereditary spherocytosis
D. Hereditary spherocytosis
Which of the following skeletal manifestations may be seen in hypovitaminosis A occurring in infancy? A. Early closure of cranial sutures B. Widening of tubular bones C. Epiphyseal overgrowth D. Widening of cranial sutures due to increased intracranial pressure
D. Widening of cranial sustures due to increased intracranial pressure
Of the following articulations, which one is most frequently involved in hemophilia? A. Knee B. Cervical spine C. Hip D. Wrist
A. Knee
If adequately performed, hemodialysis generally leads to resolution of the bone changes seen in renal osteodystrophy. If, instead, these bone changes progress, what is now believed to be the primary cause? A. Excessive removal of phosphate during dialysis B. Osteomalacia due to aluminum intoxication C. Phosphate retention during dialysis D. Excessive removal of calcium during dialysis
B. Osteomalacia due to aluminum intoxication
In which of the following occupations would would the occurrence of band-like acro-osteolysis be most accurately be considered a form of stress fracture? A. Snake handler B. Polyvinyl chloride worker C. Guitar player D. Electrician
C. Guitar player
In a patient with eosinophilic granuloma, what does a radiodense focus within a lytic cranial lesion represent? A. Target lesion B. Button sequestrum C. Rain-drop skull D. Geographic skull
B. Button sequestrum
Which of the following processes results in thickening of the long bones in osteomalacia? A. Cortical remodeling B. Subperiosteal deposition of osteoid C. Endosteal thickening D. Appositional bone growth
B. Subperiosteal deposition of osteoid
At what age is sickle cell dactylitis or “hand-foot syndrome” most common? A. Adulthood B. Adolescence C. 2 to 10 years D. 6 months to 2 years
D. 6 months to 2 years
What skull abnormalities are commonly found in hypophosphatasia? A. Widened diploe B. Sclerotic skull base C. Craniosynostosis D. Basilar impression
C. Craniosynostosis
Bismuth toxicity in adults may demonstrate which of the following radiographic abnormalities? A. Dense transverse metaphyseal bands B. Erlenmeyer flask deformity C. Osteonecrosis D. Cortical hyperostosis
C. OSteonecrosis
Magnetic resonance imaging of the lumbar spine of a 15-year old female with sickle-cell anemia demonstrate a widespread decrease in signal intensity of vertebral bone marrow, on both T1, T2 and fat-suppressed sequences. This raises the concern for? A. Bone marrow ischemia/infarction B. Iron overload C. Osteomyelities D. Normal reconversion of bone marrow
B. Iron overload
In which location within bone is conversion of bone marrow from fatty to red marrow considered unusual, at any age after the first few months of life? A. Femoral neck B. Base of the skull C. Apophyses or epiphyses D. Vertebral bodies
C. Apophyses or epiphyses
Which of the following arthritic conditions may be seen in 18-40% of patients with primary hyperparathyroidism? A. Calcium pyrophosphate crystal deposition disease B. Oseoarthritis C. Ochronosis D. Gout
A. Calcium Pyrophosphate crystal deposition disease
Which of the following is a frequent extra-osseous complication of hemodialysis, which may be severe, and, according to a study quoted in Resnick, may affect up to 80% of patients? A. Carpal tunnel syndrome B. Septicemia C. Osteonecrosis D. Soft tissue and vascular calcification
D. Soft tissue and vascular calcification
The radiographic finding of increased radiolucency of bone is best termed? A. Osteoporosis B. Osteopenia C. Osteomalacia D. Osteoclastoma
B. Osteopenia
Subchondral bone loss may be seen within joints in osteoporosis. Which disease is mimicked by magical subchondral bone resorption? A. Septic arthritis B. Tuberculous arthritis C. Rheumatoid arthritis D. Psoriatic arthritis
C. Rheumatoid arthritis
Which of the following disorders represents a high-turnover osteoporosis characterized by urinary loss of calcium and phosphorus without a compensatory increase in intestinal calcium absorption? A. Hyperparathyroidism B. Osteoporosis of immobilization or disuse C. Paget’s disease D. Idiopathic juvenile osteoporosis
B. Osteoporosis of immobilization or disuse
Which of the following compression neuropathies is particularly characteristic in acromegaly, occurring in 30% of patients, frequently bilaterally? A. Carpal tunnel syndrome B. Compartment syndrome C. Raynaud’s syndrome D. Neural foraminal encroachment
A. Carpal tunnel syndrome
A radiodense or chalky appearance of bones throughout the thorax, vertebral column, and pelvis with relative sparing of the skull and appendicular skeleton suggest which of the following: A. Osteopetrosis B. Fluorosis C. Hypervitaminosis D D. Hypervitaminosis A
B. Fluorosis
Which of the following must be included in the differential diagnosis of gas within a vertebral body? A. Dissected air from pneumothorax B. Spinal infection C. Chemical fixer artifact D. Degenerative disc disease
B. Spinal infection
Which of the following spinal syndromes may represent a form of reflex sympathetic dystrophy? A. Kummel’s disease B. Scheuermann’s disease C. Idiopathic juvenile osteoprosis D. Idiopathic juvenile kyphosis
A. Kummel’s disease