Motor Neurone Disease and Neurodegeneration Flashcards

1
Q

What is split hand syndrome?

A

APB/FDI are more severely involved than ADM

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2
Q

Which gene is the cause of 9p-linked motor neurone disease/FTD?

A

C9ORF72

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3
Q

What is the mechanism of action of riluzole?

A

reduces glutamate release

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4
Q

What is the benefit of riluzole?

A

improves outcomes in MND by about 9 months

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5
Q

What is the mechanism of action of edaravone?

A

free radical scavenger

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