Motor Neurone Disease and Neurodegeneration Flashcards
1
Q
What is split hand syndrome?
A
APB/FDI are more severely involved than ADM
2
Q
Which gene is the cause of 9p-linked motor neurone disease/FTD?
A
C9ORF72
3
Q
What is the mechanism of action of riluzole?
A
reduces glutamate release
4
Q
What is the benefit of riluzole?
A
improves outcomes in MND by about 9 months
5
Q
What is the mechanism of action of edaravone?
A
free radical scavenger