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Path Exam 1 > Morphologic Appearance of Postmortem Changes > Flashcards

Morphologic Appearance of Postmortem Changes Flashcards

1
Q

Occurs After Somatic Death

A

Autolyisis

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2
Q

Due to total Diffuse Hypoxia.

A

Somatic Death

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3
Q

Process by which post mortem bacteria break down tissues [gives color, texture changes, gas production odors]

A

Putrefaction/Decomposition

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4
Q

Which tissues will undergo autolysis first?

A

Tissues with greater concentration of proteolytic enzymes

  • gastrointestinal tract
  • pancreas
  • gall bladder
  • Liver
  • Kidneys
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5
Q

Morpholgic appearance of postmortem changes vary depending on:

A

Cause of death

Environmental and body temperature

Microbial Flora

  • Defined as mild, moderate, to severe
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6
Q

What inhibits autolysis, delaying putrefaction?

A

Cool Environmental Temperatures and refrigeration

  • Not recommended to freeze the carcass
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7
Q

Exceptions to inhibition of autolysis by refrigetartion include:

BECAUSE:

A

Ruminants forestomach

Equine Cecum and Ascending Colon

  • ingesta will continue to undergo bacterial fermentation after death►gas and heat
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8
Q

Refers to the contraction of the muscles after death

A

Rigor Mortis

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9
Q

When does Rigor mortis occur?

A

Begins at 1-6 hours post death, is persistent 1-2 days

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10
Q

What factors can accelerate the onset of rigor mortis?

A

High heat and high activity before death accelerate the onset of rigor mortis

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11
Q

Cooling of the body post mortem

A

Algor Mortis

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12
Q

What factor influences algor mortis?

A

Depends on the temperature of the body at time of death

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13
Q

This is caused by gravity pulling blood post death.

Causes a variation in color of skin, lung, heart, kidneys, liver

Some areas he tissue will be more red and in other areas pale due to that the blood was kept away

Only a post mortem change [no blood pressure]

A

Livor mortis:

AKA Hypostatic Congestion

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14
Q

When and where does post mortem clotting occur?

A

Several hours post death in the heart and vessels

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15
Q

What is post mortem clotting influenced by?

A

Ante mortem changes in the blood

i.e. warfarin poison, hereditary coagulopathies can delay or cause failure of blood to clot

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16
Q

Due to seperation of RBCs to the bottom and clotted serum at top

A

Chicken clot appearance

17
Q

Pre-Mortem Clotting characteristics:

A

Atached to vessel walls (arterial type)

Loosely attached to vessel walls (venous thrombi, may resemble post mortem clots)

Dry, duller color, laminated

18
Q

Post mortem clot characteristics:

A

Unattached to vessel walls

Shiny and wet, perfect cast of vessel lumina

19
Q

Red staining of tissue, especially the heart, arteries and veins

A

Hemoglobin imbibition

20
Q

What causes Hemoglobin imbibition?

A
  • hemoglobin is released by lysed RBCs and penetrates the vessel wall and extends into the adjacent tissues
21
Q

Tissue sensitivity to hypoxia is dependant upon:

A

Energy demands of the cell and/or its ability to utilize anaerobic glycolysis as a source of energy

Neurons>Hepatocytes,Myocardium, Renal Epithelium>Fibroblast, Epidemia, Skeletal Muscle

22
Q

True or False:

Hemoglobin staining can occur in acute intravascular hemolysis

A

TRUE

23
Q

Identify

A

Bile Imbibition

24
Q

How does bile imbibition occcur?

A

Bile in the gallbladder starts to penetrate the wall and stains the adjacent tissue yellowish to greenish brown

25
Q

What tissues are affected by bile imbibition?

A

liver

intestines

26
Q

Results from post mortem bacterial gas formation in the lumen of the GI tract

A

Bloating

27
Q

True or False:

A canine will bloat faster postmortem than a bovine

A

FALSE:

  • Herbivores bloat faster d/t microbes/gas distention from bacteria
28
Q

What must you differentiate postmortem bloating from?

A

Tympany- a pre-mortem change

29
Q

What can cause clouding of the lens of the eye?

A

Post-mortem- cold temperatures

Pre-mortem: cataracts

30
Q

Greenish-black discoloration of tissues post-mortem

A

Pseudomelanosis

31
Q

What causes Pseudomelanosis?

A
  • decomposition of blood by bacterial action forming hydrogen sulfide with iron
32
Q

Tissues affected by psuedomelanosis?

A
  • Gut
    • and Gut wall
  • Kidney
  • Liver
  • Spleen

Path Exam 1 (9 decks)

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