more qs Flashcards
2 chemo to not give with aprepitant
ifosphamide and etoposide
Mentzner index
MCV/rbc nymber. if <13, that. if >13, iron
what is APML histology
bilobed or folded nucleus with azurophiic granules and anger rods
t(6:9)
AML, often with FLT3
what probs are AML 3q with
megakarycotytes
what factors are in 4 factor activated prothrombin complex
2, 7, 9 and 10
most common secondary cancer after irradiation for solid tumor in childhood (in first 20 years)
osteosarcoma
graphical display to determine I fa change has resulted in improvement
run chart or trend chart
tool for organizing and displaying theory of improvement
driver diagram
chart that identifies areas of greatest improvement
Pareto
chart that distinguishes between special and common variations in system
shewhart
BCOR ITD- cancer and what you screen for
clear cell sarcoma. bone scan and MRI brain
stage IV wilms with incomplete lung response after 6 cycles
add cy/etop
congenital b12 def that presents with brain atrophy, hypotonia proteinuria between 1 and 5
ismerslund-grasbeck
b12 problem presenting in first year of life with failure to thrive, vominting, weakness
Transcobalamin II def
age you need to decrease dose for dactino
<12 mo
inheritance: antithrombin deficiency
dominant
3 diseases that can coinhert with dense granule deficiency
WAS< hermansky padlock, chediak higashi
how to confirm LAD II
flow for Silly lewis x (SLEX aka CD15a) which needs fucose
what do you look for when flowing for LAD1
CD11/CD18
blood product for congenital protein S or C deficiency
must do FFP
met common oocation- ewings
distal femur and pelvis
most common location- osteosarcoma
distal femur, proximal tibia, proximal humerus
which direct thrombin inhibitor needs liver metabolism and which is kdiney
argatroban- liver. BZival- renal
best test to monitor direct tthobin
APTRT
most common causes (1-3) for DKC
1) bone marrow failure 2) pulmonary fibrosis 3) malignancy
costello syndrome aka faciocutaneouskleatl syndroem- increased risk for what
RMS, bladder, and vestibular schwannoma
4 syndromes that increase risk for RMS
Li fraumeni, NF1, costello, BWS
cancer risks for someone with HyperIgM syndrome
carcinoma of liver and bile duct, and neuroectodermal tumors of liver and panreas
most common bacterial infection in red blood cells
yersinia (or gram -
what bugs grow in plt
gram +
antibody in IPT
GP2b/3a, usually IgG
