hsct Flashcards

1
Q

Dose auto CD34

A

2-5 x 10^6 cd34+/kg

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2
Q

dose allo cd34

A

4-8x10^6 cd34/kg

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3
Q

dose cord cd34

A

more than 1.5-2 x10^5 cd34/kg

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4
Q

TBNC dose after BM harvest allo

A

2-6 x 10^6 MNC/kg

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5
Q

cord TNC dose goal

A

more than 4x10^7 TNC/kg, go over 5 for high mismatch

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6
Q

what do you want the CD34 level to be before peripheral collection

A

more than 20 cells per microL

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7
Q

mechanism plerixafor

A

CXCR4 blocker that [aks at 5-11 hours

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8
Q

target CD4 for haplo or T cell depleted

A

more than 5-10 x 10^6 CD34/kg

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9
Q

goal T cells in the t cel depleted or halo T cell product

A

less than 1* 10^5 CD3 or alpha beta CD3 per kg

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10
Q

dose of TNC for PT cy

A

more than 4 * 10^8 MNC/kg

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11
Q

quickly falling chimerism hat do you do

A

wean immunosuppression EXCEPT sAA- then you increase

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