More Misc Flashcards
Definition of AKI:
- Serum creatinine increase of 0.3+ in 48 hours
- Serume creatinine increase of 150% of baseline in 7 days
- Urine volume <0.5 mL/kg/hr
RBC casts
acute glomerulonephritis
Muddy brown or epithelial casts
ATN
WBC casts
AIN or pyelonephritis
Narrow waxy casts
chronic ATN/glomerulonephritis
Broad waxy casts
ESRD
Fatty casts “maltese crosses”, oval fat bodies
nephrotic
eospinophils
ATN
MC form of AKI
Prerenal
Define acute tubular necrosis:
prolonged or severe ischemia caused by a prerenal condition, it eventually leads to an intrarenal processes
Define tubulointerstitial nephritis
inflammatory of allergic response in interstitium with sparing of the glomeruli and blood vessels
MCC of tubulointerstitial nephritis
drug hypersensitivity
Tx tubulointerstitial nephritis
prednisolone x 1-2 weeks
TINU syndrome
interstitial nephritis + uveitis
BUN/Cr ratio: prerenal
> 20:1
BUN/Cr ratio: intrarenal
<10:1
BUN/Cr ratio: post-renal
early >20:1 and late <10:1
MCC of ESRD?
DM
CKD Stage 1
> 90
CKD Stage 2
60-89
CKD Stage 3
30-59
CKD Stage 4
15-29
CKD Stage 5
<15 or dialysis
Glomerulonephritis AKA
nephritic syndrome
What kidney disease is associated with cola colored urine?
nephritic
MCC AGN worldwide?
IgA neuropathy (Berger’s)
Young male presents within 24-48 hours after URI or GI infection with symptoms of nephritic syndrome?
IgA nephropathy (Berger’s)
Dx of IgA nephropathy (Berger’s)
+ IgA mesangial deposits on immunostaining
Tx Berger’s
ACE +/- corticosteroid
Post-infectious glomerulonephritis MC after?
GABHS
2-14 year old boy with facial edema 3 weeks after strep with scanty, cola-colored/dark urine?
Post-infectious glomerulonephritis
Dx of post-infectious glomerulonephritis
increased ASO, low serum complement
kidney failure + hemoptysis
Good pasture’s disease
nephritic syndrome gold standard
renal biopsy
Nephrotic CM
heavy protienuria (>3 g/d), hypoalbuminemia, hyperlipidemia, edema
MCC of nephrotic syndrome in kids
minimal change disease
MCC overall of nephrotic syndrome in adults?
DM
gold standard for nephrotic syndrome
24 hour urine protein collection
Tx nephrotic syndrome
ACE/ARB, loop for edema, statins for hyperlipidemia
Others in house have head cold?
bronchiolitis
CXR bronchiolitis
hyperinflation, patchy atelectasis
Bronchiolitis tx
no tx
Barky cough
croup
MC infection of middle respiratory tract in kids
croup
Laryngitis in older kids
croup
viral or bacterial? croup
viral
When are symptoms worse with croup?
night
Westley croup severity score?
Level of consciousness, cyanosis, stridor, air entry, retractions
Steeple sign
Croup
Tx mild croup
observe –> antipyretics, vaprizer, fluids
Tx croup with stridor at rest or signficant discomfort
oral dexamethasone x 1 dose OR
racemic epinephrine for resp. distress
Whoop coughing
pertussis
Dx pertussis
Pertussis PCR
tx pertussis
Azithromycin
Extrinsic causes of pleural effusion are called?
transudative
Intrinsic causes of pleural effusion are called?
exudative
Transudative causes of pleural effusion?
liver disease/cirrhosis, cardiac disease/CHF, renal disease/chronic renal failure
Exudative causes of pleural effusion?
malignancy, pneumonia, TB, PE
Initial test for pleural effusion?
x-ray
Tx for pleural effusion?
thoracocentesis
Thoracocentesis procedure:
insert 1-2 intercostal spaces below height of effusion; not below 9th rib
Do you go above or below rib in thoracocentesis?
above
Thoracocentesis: pale yellow
usually transudative
Thoracocentesis: yellow-green
RA
Thoracocentesis: blood or red
malignancy or asbestosis
Thoracocentesis: brown, anchovy psate
amebic liver abscess
Thoracocentesis: black
aspergillus infection
Thoracocentesis: putrid odor
anaerobic abscess
Blunting of costophrenic angles
pleural effusion
3 d’s of endometriosis
dysmenorrhea, dyschezia, dyspareunia
MC site for endometriosis?
ovary
Triad of endometriosis
pelvic pain; fixed and firm adnexal mass; tender nodularity in cul-de-sac and uterosacral ligaments
Endometriosis: US
ground glass appearance of implants
Tx: endometriosis
OCPs, medroxyprogesterone acetate; NSAIDs
MC type of benign ovarian tumor
epithelial
MC type of epithelial ovarian tumor
Serous
Best modality for assessing ovarian tumors
US
PROM definition:
at least 1 hour prior to active labor (at or after 37 weeks gestation)
Prolonged PROM:
18+ hours before onset of labor
Dx PROM:
avoid digital vaginal exam; sterile speculum exam and confirmation via nitrazine test (detects pH –> alkaline if amniotic) and fern test (detects salt crystals in amniotic fluid)