Mood stabilizers Flashcards

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1
Q

Tx of lithium toxicity

A

Fluid resuscitation Dialysis if [Li] > 4.0

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1
Q

SJS

A

Lamotrigine

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1
Q

Therapeutic level of valproate

A

6-12

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2
Q

Agranulocytosis

A

Carbamazepine

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4
Q

Increases or decreases [Li]: Dehydration

A

Increases

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4
Q

Skin rash

A

Carbamazepine

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5
Q

Hyponatremia

A

Carbamazepine

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6
Q

Monitor in patients on Li:

A

TFTs GFR/kidney function Blood levels of Li

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7
Q

Symptoms of lithium toxicity

A

Fine tremor AMS Convulsions

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7
Q

Low platelets

A

Valproic acid

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9
Q

Lethal range of Li

A

>2.0

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10
Q

Good for mixed episodes and rapid cycling

A

Carbamazepine Valproic acid

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11
Q

Neural tube defects

A

Carbamazepine, valproic acid

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13
Q

Tx for bipolar preggo

A

Clonazepam

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14
Q

Increases or decreases [Li]: Impaired renal function

A

Increases

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14
Q

Aplastic anemia

A

Carbamazepine

16
Q

Increases or decreases [Li]: NSAIDs

A

Decreases

17
Q

Good for trigeminal neuralgia

A

Carbamazepine

18
Q

Toxic range of Li

A

>1.5

19
Q

6 factors affecting lithium levels

A

NSAIDs (decrease [Li]) ASA Dehydration (increases [Li]) Salt deprivation (increases [Li]) Impaired renal function (increases [Li]) Diuretics

21
Q

Increases or decreases [Li]: Salt deprivation

A

Increases

22
Q

Therapeutic level of carbamazepine

A

60-120

23
Q

EKG findings with lithium toxicity

A

T wave flattening or inversion + U waves

24
Q

Therapeutic range of Li

A

0.6-1.2

25
Q

Hemorrhagic pancreatitis

A

Valproic acid

26
Q

LFTs needed

A

Carbamazepine, valproic acid

27
Q

CI to lithium

A

Severe renal disease Pregnancy/breastfeeding Diuretics Digoxin MI Myasthenia gravis

28
Q

MC SE of carbamazepine

A

Rash