Antidepressants Flashcards

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0
Q

Treatment of enuresis

A

TCAs

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0
Q

TCA with least sedating effects

A

Desipramine

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0
Q

CI in hypertensives

A

Venlafaxine

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1
Q

Good for depression with insomnia

A

Trazadone

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3
Q

Weight gain

A

Mirtazapine

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3
Q

Treatment of hypertensive crisis with MAOI

A

Phentolamine

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4
Q

Useful for refractory depression

A

Venlafaxine Trazadone/nefazodone Mirtazapine

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4
Q

ADs with highest risk for serotonin syndrome

A

Sertraline and fluvoxamine

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5
Q

TCA that’s most serotonin specific

A

Clomipramine

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5
Q

SSRI with highest risk of GI upset

A

Sertraline

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7
Q

AD with least sexual side effects

A

Bupropion

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8
Q

TCA with least orthostatic hypotension

A

Nortryptiline

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9
Q

SSRI only approved for OCD

A

Fluvoxamine

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11
Q

MOA TCAs

A

Inhibit reputable of NE and 5HT

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12
Q

AD that causes withdrawal

A

Venlafaxine Can occur after missing 1-3 doses (Flu like symptoms, electric-like shocks or zaps)

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12
Q

Don’t take with St. John’s wart

A

Venlafaxine

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13
Q

SSRI with no need to taper

A

Fluoxetine

13
Q

Good for depression in underweight people

A

Mirtazapine

14
Q

Caveat of mirtazapine for sedation

A

Sedating at 15 mg or less Above 15 mg it increases NE and is less sedating

15
Q

SARI

A

Trazadone and nefazodone (serotonin antagonist and reuptake inhibitor)

16
Q

AD that can exacerbate psychosis

A

Bupropion (Dopaminergic effects)

18
Q

AD you can’t give to an anorexic/bulimic pt

A

Bupropion

19
Q

SSRI with stimulant properties

A

Paroxetine

19
Q

Priapism

A

Trazadone

21
Q

AD with fewest drug-drug interactions

A

Citalopram

22
Q

AD with sedation as major SE

A

Trazadone and nefazodone

23
Q

AD you can’t give to pt with seizures

A

Bupropion

24
Q

Agranulocytosis

A

Mirtazapine

26
Q

SNRI

A

Venlafaxine (why you can’t give it to hypertensive patients)

27
Q

CI to bupropion

A

Seizures and active eating disorders MAOI use

28
Q

NASA

A

Mirtazapine (NE and 5HT antagonist)

30
Q

CI to TCAs

A

Conduction abnormalities

31
Q

SSRI with most serotonin specificity

A

Paroxetine

32
Q

Pt stops taking AD and develops body aches, fever, N/V

A

Venlafaxine withdrawal

33
Q

TCA with least anticholinergic effects

A

Desipramine

34
Q

SSRI with longest half life

A

Fluoxetine

36
Q

AD with most drug-drug interactions

A

Paroxetine

37
Q

Pt on phenelzine with persistent depression. Which ADs can you not give?

A

SSRI or bupropion

39
Q

Pt stops taking AD and complains of shock-like pains

A

Venlafaxine withdrawal

40
Q

NDRI

A

Buproprion (remember dopamine = worsened psychosis)