Mood Stabilisers Flashcards

1
Q

Valproate

A

GABA agonist and NMDA antagonist

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2
Q

Gabapentin

A

Unknown
Doesn’t do anything with GABA
High affinity for voltage-gated calcium channels, especially alpha-2-delta-1,
which inhibit the release of excitatory neurotransmitters in the presynaptic area.

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3
Q

Topiramate

A

GABA agonist, NMDA antagonist, and Na channel stabiliser

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4
Q

Carbamazepine

A

Stabilises Na channels

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5
Q

Phenytoin

A

Stabilises Na channels

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6
Q

Lamotrigine

A

NMDA antagonist and stabilises Na channels

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7
Q

Pregabalin

A

Potent ligand for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system

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