Mood Stabilisers Flashcards
1
Q
Valproate
A
GABA agonist and NMDA antagonist
2
Q
Gabapentin
A
Unknown
Doesn’t do anything with GABA
High affinity for voltage-gated calcium channels, especially alpha-2-delta-1,
which inhibit the release of excitatory neurotransmitters in the presynaptic area.
3
Q
Topiramate
A
GABA agonist, NMDA antagonist, and Na channel stabiliser
4
Q
Carbamazepine
A
Stabilises Na channels
5
Q
Phenytoin
A
Stabilises Na channels
6
Q
Lamotrigine
A
NMDA antagonist and stabilises Na channels
7
Q
Pregabalin
A
Potent ligand for the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system