Adverse Effects

Question 1

Which sex is more at risk of QTc prolongation?

Answer 1

Female

Question 2

Commonest side effect of methylphenidate

Answer 2

Insomnia

Question 3

What drug is helpful for treating SEs from reboxetine

Answer 3

Doxazosin

Question 4

What % tardive dyskinesia cases are reversible with dose reduction?

Answer 4

50-55%

Question 5

SSRi most a/w erectile dysfunction

Answer 5

Paroxetine

Question 6

Agranulocytosis occurs most commonly during the first how many weeks of Rx

Answer 6

18

Question 7

Worst class of antideps for weight gain

Answer 7

TCAs

Question 8

Which receptor type is involved in hypersalivation with clozapine use

Answer 8

Muscarinic

Question 9

Anticholinergics are helpful for which SE

Answer 9

Dystonia

Question 10

Most commonly a/w priapism

Answer 10

Trazodone

Question 11

Which benzo is worst in OD

Answer 11

Alprazolam

Question 12

Principle cause of death in TCA OD is

Answer 12

Cardiac arrhythmia

Question 12

Principle cause of death in TCA OD is

Answer 12

Cardiac arrhythmia

Question 13

Sexual SEs with SSRIs are due to what receptor

Answer 13

5HT2

Question 14

Which diuretic can help with lithium induced polyuria without causing toxicity?

Answer 14

Amiloride

Question 15

Patients on clozapine/olanzapine should have lipids checked how often for the 1st year?

Answer 15

3 monthly

Question 16

Most common adverse effect of valproate

Answer 16

Diarrhoea

Question 17

What is the treatment for cheese+MAOI induced hypertension?

Answer 17

Phentolamine

Question 18

Lithium induced hypothyroidism is most common in

Answer 18

Young females

Question 19

Which drug is a/w nephrolithiasis

Answer 19

Topiramate

Question 20

Risk of fatal agranulocytosis in clozapine patients

Answer 20

1/4250

Question 21

Which receptor is reponsible for drug induced weight gain

Answer 21

5HT2C

Question 22

Bupropion effect on weight

Answer 22

Weight loss

Question 23

Anxiety and agitation in the first few weeks of SSRIs are due to what

Answer 23

Overstimulation of 5HT2 receptors in limbic system

Question 24

What happens to the plasma levels of both TCAs and APsys if co-administered

Answer 24

Both increase

Question 25

Which SSRI is most expressed in breast milk

Answer 25

Fluoxetine

Question 26

Sweating due to venlafaxine can be treated with what

Answer 26

Alpha-adrenergic blocker Terazosin

Question 27

Postural hypotension due to TCAs is caused by

Answer 27

Alpha adrenergic blockade

Question 28

TCA with most antihistaminergic activity

Answer 28

Doxepin

Question 29

ABx that can cause serotonin syndrome if combined with MAOi

Answer 29

Linezolid

Question 30

Confusional state caused by antipsychotics is due to

Answer 30

Muscarinic blockade

Question 31

SE of mianserin requiring monitoring

Answer 31

Bone marrow suppression

Question 32

Botox can be helpful to treat

Answer 32

Tardive Dystonia

Question 33

Tardive dystonia occurs after

Answer 33

Months to years of treatment

Question 34

Which type of antipsychotic has a lower risk of TD?

Answer 34

Atypicals

Question 35

Which antidepressant is contraindicated in closed angle glaucoma

Answer 35

Paroxetine

Question 36

Floppy baby syndrome a/w

Answer 36

Benzos

Question 37

In treating serotonin syndrome, antagonism of which receptor is helpful for controlling neuro symptoms?

Answer 37

5HT2A