Mood Disorders and Drugs Flashcards

1
Q

Tricyclic

Selective NE reuptake inhibitor

A

Desipramine (Norpramin)

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2
Q

Tricyclic

Mixed action NE/5HT reuptake inhibitor

A

Imipramine (Tofranil)

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3
Q

MAO inhibitor

A

Phenelzine (Nardil)

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4
Q

SSRI

A

Fluoxitine (Prozac)

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5
Q

SSRI

A

Sertraline (Zoloft)

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6
Q

SSRI

A

Escitalopram (Lexapro)

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7
Q

SNRI

blocks reuptak of 5HT and NE

does NOT affect adrenergic, histaminergic, or cholinergic receptors (LESS “Shotgun effect” = less side effects)

A

Venlafaxine (Effexor, Effexor XR)

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8
Q

Blocks pre-synaptic a2 receptors (autoreceptors and heteroceptors) preventing self mediated regulation fo NE and 5HT levels by the neurons and increasing synaptic cleft NE and 5HT:

A

Mirtazapine (Remeron)

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9
Q

Used to treat bipolar disorder

no effect on normal subjects

unknown MOA, likely post synaptic neuron involvement

readily absorbed from GI tract, 95% renal excretion

LOW therapeutic index

A

Lithium Carbonate (Eskalith)

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10
Q

Anticonvulsant used to treat bipolar disorder

better than Lithium for rapid cycling bipolar disorder

appropriate first line tx for some

can be combined with Lithium for pts who have failed either treatment alone

A

Valproic acid (Depakote Depakene)

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11
Q

Anticonvulsant approved by FDA for prophylaxis of bipolar disorder

A

Carbamezepine (Tegretol)

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