Barbs, Benzos, and other anxiolytics and hypnotics

Question 1

Barbiturate

treats tonic-clonic seizures

Answer 1

Phenobarbital

Question 2

barbiturate

Answer 2

Pentobarbital

Question 3

barbiturate

very lipid soluble (rapid penetration) –> induction of anesthesia

Answer 3

Thiopental

Question 4

benzo

Answer 4

Diazapam

Question 5

benzo

Answer 5

Lorazepam

Question 6

benzo

short 1/2 life ~4hrs –> w/d sx between doses

Answer 6

Triazolam

Question 7

benzo

Answer 7

Alprazolam

Question 8

benzodiazapine binding site antagonist

tx of benzo OD or postanesthetic respiratory supression

Answer 8

Flumazenil

Question 9

selective anxiolytic

no direct GABA action

partial agonist at brain 5HT1a receptors

affinity for DA D2 receptors

minimal abuse liabillity

Answer 9

Buspirone

Question 10

Non benzo, benzo-receptor agonist for sleep (ambien)

Answer 10

Zolpidem

Question 11

melatonin M1 M2 receptor agonist

novel sleep aid

Answer 11

Ramelteon

Question 12

Patient is relaxed, unconcerned with surroundings, and is fully functional:

Answer 12

anxiolytic

Question 13

decreased activity, moderates excitement, and calms patient, although patient is awake

Answer 13

sedative

Question 14

produces drowsiness and facilitates onset and maintenance of sleep; patient may be easily aroused:

Answer 14

hypnotic

Question 15

a state where there is loss of conciousness from which the patient cannot be aroused:

Answer 15

general anesthesia