Mood Disorders

Question 1

1st line treatment in mild to moderate depression

Answer 1

SSRI or CBT or IPT

Question 2

First line tx of moderate to severe depression

Answer 2

SSRI and CBT or IPT

Question 3

Give examples of SSRI’s used in depression

Answer 3

Fluoxetine, Sertraline, Citalopram, Paroxetine

Question 4

Give examples of tricyclic Antidepressants

Answer 4

Amitriptyline, Imipramine

Question 5

Give examples of monoamine oxidase inhibitors used in depression

Answer 5

Phenelzine, Moclobemide

Question 6

Give an example of Serotonin and Noradrenaline Reuptake Inhibitor (SNRI) used in depression

Answer 6

Venlafaxine

Question 7

Give an example of Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)

Answer 7

Mirtazapine

Question 8

Give an example of Melatonin agonist and Serotonin antagonist used in depression

Answer 8

Agomelatine

Question 9

Treatment of acute episode of mania

Answer 9

. Lithium
• Valproate
• Atypical antipsychotic (olanzapine, risperidone)

Question 10

Treatment of acute episode of bipolar depression

Answer 10

Valproate
• Quetiapine
• Lamotrigine
• Lithium

Question 11

Treatment cor maintenance of bipolar disease

Answer 11

Lithium**
• Valproate **
• Olanzapine

Question 12

Side effects of Lithium drugs

Answer 12

Abdominal pain, nausea, metallic taste in the
mouth, fine tremor, thirst, polyuria, impaired urinary concentration,
weight gain and oedema

Question 13

Side effects of valproate

Answer 13

Abnormal eye movement, blood and bone marrow problems,
concentration problems, confusion, deafness, extrapyramidal side effects

Question 14

Most common side effects of lamotrigine

Answer 14

skin rash including Stevens-Johnson syndrome

Question 15

Side effects of olanzapine

Answer 15

postural hypotension, abnormal gait, wieght
gain

Question 16

Contraindication of valproate

Answer 16

Women in child bearing period