mood (depression, mania) Flashcards
cyclothymic criteria
multiple periods of hypomanic & depressive sxs that do NOT meet criteria for full episodes for over 2y (w/o euthymic for more than consecutive 2m)
bipolar depression FDA approved meds
symbyax, seroquel, latuda
remission from MDE per APA guidelines
at least 3w absence of dysphoria + anhedonia AND <=3 remaining sxs
risk of bipolar with dx in 1st degree relative
10%
minimum duration for hypomanic v manic episode
hypomanic = 4d manic = 1w or ANY if hospitalized
basic manic/hypomanic criteria
elevated/irritable mood + 3 of dec need for sleep, inc activity/agitation, out of character risky activities, grandiosity, talkativeness, FoI, distractability
neuro finding in late onset mania
R hemispheric & subcortical lesions…. higher relative mortality than pts w mania throughout adulthood
suicide rate in bipolar
10-15%
bipolar first episode is most often which type
depression
are depressive/manic episodes more common in each gender
gender ratios in bipolar 1 vs 2
M: manic >= depression
F: depression > manic
1: F = M
2: F > M
when in gestation is VPA teratogenic
3-6 weeks (before aware of pregn)
define rapid cycling specifier
more common in M or F?
> =4 major depressive, manic, or hypomanic episodes in past year
F > M
effect of Li in PD
may be neuroprotective long term?!
% of ppl w CV dz who develop depression?
25+
lamictal FDA indication?
bipolar 1 maintenance
adjustment prognosis for adults v teens
teens more guarded bc more likely to develop major mental illness
adults prognosis good once stressor terminated