Monoclonal Antibodes Flashcards
1
Q
Outline the hybridoma method for the production of monoclonal antibodies that will target a particular protein.
A
- Antigen is injected into the mouse
- immune response occurs
- B lymphocytes exctraced from the mouse
- plasma cells fuse with the cancer e cells forming hybridoma cells
- hybridoma cells are cloned and cultures
- they are screened for cells secreting desired antibody
2
Q
Suggest why repeated treatment with monoclonal antibodies cause the treatment to be less effective
A
Monoclonal antibodies detected as foreign and body stimulates an allergic/ immune response
