monobactem Flashcards
1
Q
aztreonam
A
g- rods klebsiella pseudomonas serratia also P. aeruginosa
2
Q
not active against
A
g+ bacteria + anaerobes
3
Q
MOA
A
cell wall inhibitor
bind to PBP 3
4
Q
synergism
A
aminoglycosides
5
Q
administration
A
IV +IM
6
Q
excretion
A
renal tubular
7
Q
toxicities
A
1- headache 2- vertigo 3- superinfection 4-hepatotoxicity (rarely) 5- skin rash 6- no cross allergy with penicillins
8
Q
safe for
A
patients with penicillin allergy
9
Q
treatment
A
sepsis
pneumonia
meningitis
