Monoamine Oxidase Inhibitors (MAOIs)

Question 0

Tranylcypromine (Parnate)

Answer 0

Irreversibly inhibits MAO A and B

Question 1

Phenelzine (Nardil)

Answer 1

Irreversibly inhibits both MAO A and B

Question 2

MAOIs

Answer 2

Oral absorption, liver metabolism. Irreversibly inhibit MAO-A or B. SE: hypertensive crisis due to accumulation of tyramine (Tx w/alpha blocker). Avoid alcohol and food high in tyramine such as aged cheese, bean curd, sausages (she mentioned beer, brats, red wine, cheese).