Mono and Lyme Disease

Question 1

Atypical lymphocytes (“Downey cells”) appear in circulation (mostly T cells) in which infection?

Answer 1

Epstein-Barr virus; T Cells in the periphery and B cells in the germinal center

Question 2

19 year old patient and the presence of heterophile antibodies is a key factor in diagnosis in which disease? What test is it followed up with?

Answer 2

EBV; serology

Question 3

How do you screen for mono in a child?

Answer 3

Screen for antibodies to virus capsid or other virus antigens

Question 4

What test should be done if you suspect Lyme disease?

Answer 4

serology with ELIZA and reflex Western Blot test; WATCH FOR FALSE POSITIVES with mono, syphilis, SLE, RA (i.e. this is mostly a clinical diagnosis)

Question 5

What is the treatment for Lyme disease?

Answer 5

For patient with symptoms, amoxicillin or

doxycycline for 10-21 days