Molluscum contagiosum Flashcards

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1
Q

Define molluscum contagiosum.

A

Common viral skin infection that causes localised clusters of umbilicated epidermal papules.

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2
Q

What type of virus is molluscum contagiosum?

A

Pox virus, transmitted by contact

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3
Q

How common is molloscum contagiosum?

A

Mostly in chilren - ~10% prevalence

More common in tropical climates
More common in adults with HIV

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4
Q

What are some risk factors for molluscum contagiosum?

A
  • Atopic dermatitis/other skin barrier problems
  • HIV infection - becomes extensive
  • Tropical climate
  • Swimming
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5
Q

How is MC transmitted?

A
  • Direct skin to skin contact
  • Indirect contact by shared towels
  • Auto-inoculation by scratching or shaving
  • Sexual transmission
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6
Q

What is the incubation time of MC?

A

usually 2 weeks - up to 6 months

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7
Q

What are the clinical features of MC?

A
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8
Q

What are the types of MC virus?

A

MCV1 and 1v - children
MCV2 - groin or generalised immunocompromised
MCV3 - rare at any age

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9
Q

What is the histopathology of MC?

A

Henderson-Patterson bodies - abnormal keratinocytes heavily stained with H&E stain

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10
Q

What are the clinical features of molluscum contagiosum?

A

Clusters of small round papules
1-6mm in size
White, pink or brown in colour
Waxy/shiny look
Umbilicated - central pit
Papule contains white cheesy material
In moist areas - armpit, knees, groin, genital
NOT on palms and soles

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11
Q

What is the prognosis with MC?

A

Appear within a few days - 6 weeks after infection
Natural course lasts 2-4yrs with spontaneous clearance
Prolonged if immunocompromised

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12
Q

What are the complications of MC?

A

Secondary bacterial infection from scratching
Conjunctivitis
Secondary eczema
Widespread rash e.g. in HIV
Pitted scarring - may occur by itself or as a result of its treatment by surgery

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13
Q

What investigations would you do for MC?

A

99% clinical diagnosis

  • Curettage biopsy
  • Swabs for culture if infected
  • Assess for HIV in resistant disease
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14
Q

What is the management of MC?

A

Medical:

  • Antiseptic hydrogen peroxide cream
  • Benzoyl peroxide
  • Salicylic acid
  • Tretinoin topical
  • Cantharidine solution
  • Steroids for secondary dermatitis

Physical

  • Cryotherapy, cautery or curettage - likely to scar and may even cause spread of disease. Weekly treatments over 6-8 weeks may be needed.
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15
Q

What is the diagnosis?

A

Molluscum contagiosum

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