Molluscum contagiosum Flashcards
Define molluscum contagiosum.
Common viral skin infection that causes localised clusters of umbilicated epidermal papules.
What type of virus is molluscum contagiosum?
Pox virus, transmitted by contact
How common is molloscum contagiosum?
Mostly in chilren - ~10% prevalence
More common in tropical climates
More common in adults with HIV
What are some risk factors for molluscum contagiosum?
- Atopic dermatitis/other skin barrier problems
- HIV infection - becomes extensive
- Tropical climate
- Swimming
How is MC transmitted?
- Direct skin to skin contact
- Indirect contact by shared towels
- Auto-inoculation by scratching or shaving
- Sexual transmission
What is the incubation time of MC?
usually 2 weeks - up to 6 months
What are the clinical features of MC?
What are the types of MC virus?
MCV1 and 1v - children
MCV2 - groin or generalised immunocompromised
MCV3 - rare at any age
What is the histopathology of MC?
Henderson-Patterson bodies - abnormal keratinocytes heavily stained with H&E stain
What are the clinical features of molluscum contagiosum?
Clusters of small round papules
1-6mm in size
White, pink or brown in colour
Waxy/shiny look
Umbilicated - central pit
Papule contains white cheesy material
In moist areas - armpit, knees, groin, genital
NOT on palms and soles
What is the prognosis with MC?
Appear within a few days - 6 weeks after infection
Natural course lasts 2-4yrs with spontaneous clearance
Prolonged if immunocompromised
What are the complications of MC?
Secondary bacterial infection from scratching
Conjunctivitis
Secondary eczema
Widespread rash e.g. in HIV
Pitted scarring - may occur by itself or as a result of its treatment by surgery
What investigations would you do for MC?
99% clinical diagnosis
- Curettage biopsy
- Swabs for culture if infected
- Assess for HIV in resistant disease
What is the management of MC?
Medical:
- Antiseptic hydrogen peroxide cream
- Benzoyl peroxide
- Salicylic acid
- Tretinoin topical
- Cantharidine solution
- Steroids for secondary dermatitis
Physical
- Cryotherapy, cautery or curettage - likely to scar and may even cause spread of disease. Weekly treatments over 6-8 weeks may be needed.
What is the diagnosis?
Molluscum contagiosum