Molecular Old Exam 1 Flashcards
Eukaryotic DNA replication
is activated at different times during S phase, depending on chromatin structure
T/F The majority of the human genome is protein coding
FALSE
T/F To be functional, a chromosome must contain an origin of replication, a centromere and telomeres
True
Genes in different species that are similar in both sequence and function due to common ancestry are called
Homologues
A duplicated gene that has become irreversibly inactivated by multiple mutations is called a
Pseudogene
The different combinations of modifications added to histone tails by reader writer enzymes is referred to as
Histone code
T/F Centromeric heterochromatin contains the variant histone H2AX and must contain alpha satellite DNA
FALSE
Which statement is concerning homologous recombination is true?
It requires a 3’ end to initiate strand invasion
T/F UV radiation from sun can produce a covalent linkage between two adjacent purines.
FALSE
-free radicals do this
T/F Non-homologous end joining does not require a template and creates a mutation at site of repair.
True
A transient DNA intermediate that contains four dna strands from two different dna helices is a
Holliday junction
After strand invasion has occurred, the pt of exchange can move along the helix and result in different amounts of heteroduplex dna through the process of
Branch migration
Correct statement
The mismatch repair system prevents inappropriate recombination events
Which is false
Nondisjunction events occur most often in sperm development and increase with advanced paternal age
-females this is true for
The number of gametes after one round of mammaliain meiosis is _____ female gamete or _____ male gametes
1;4
