Cell Bio Flashcards
Which of the following DOES NOT inhibit microtubular polymerization?
Taxol
The structure of bio membranes best described
A fluid-mosaic of proteins interspersed in a phospholipid bilayer
Simple, non-ciliated columnar epithelium is most likely found associated with?
Digestive tract
Which of the following statements correctly describe the nucleolus?
It is the site for synthesis of rRNA
During the cell cycle, there are several checkpoints to ensure everything is ready prior to. One is the microtubule check point; this specific occurs during which stage?
M
Nuclear lamins are intermediate filaments that:
Line the inner aspect of the nuclear envelope
A connexon is a structural component of the
Gap Junctions
T/F Each microtubule consists of thirteen protofilaments?
True
Which of the following junctional complexes provide a tight seal between adjacent epithelial cells and serves as a barrier for paracellular transport?
Zonula occludens
Junctional complexes are associated with which cellular domain?
Basolateral
Which of the following group of cell adhesion molecules is calcium independent and mainly involved in cell-extracellular matrix and to the internal cytoskeleton?
Integrins
Which of the following categories of membrane proteins are represented by proteins that have a hydrophobic domain and two hydrophilic domains?
Transmembrane proteins
SNARE, SNAP and VAMP are associated with which of the following processes?
Vesicle and target membrane docking
Which of the following groups of CAMs functions through carbohydrate binding?
Selectins
T/F Some cargos are stored in secretory vesicles within the cytoplasm and released in response to a specific extracellular signal such as a hormone. This is referred to as constitutive.
False
Transport complexes that serve to transport proteins across outer mitochondrial membrane in the intermembrane space, from which they may be further transported across the inner membrane and perhaps into the matrix are referred to as
TOMs
Synthesis of materials required for mitosis occurs during which stage of cell cycle?
G2
Transitional epithelium associated with
Urinary
During which part of the cell cycle to chromosomes consists of two chromatids each?
Late G2
Which of the following promotes the formation of stable complexes between exportins and their cargo protiens?
Ran-GTP
Linker DNA is associated with which histone
H1
In the cytoplasm, as part of the process for moving materials across the nuclear membrane of the following converts Ran-GTP to Ran-GDP
Ran-GAP
Which of the following motor molecules consists of one head domain binding to actin and one tail domain binding to the cell membrane of a cargo vesicle?
Myosin I
Which of the following statements is TRUE
Coatemers are removed shortly before docking with their target membranes
Which of the following is located within the membrane of phospholipid bilayer and moderates membrane fluidity by restricting movement
Cholesterol
Which of the following forms caps and prevents elongation of actin filatments
Cytochalasin
Which of the following is not a type of intermediate filament
Fibronectin
Which type of membrane transport molecule carries 2 molecules simultaneously in opposite directions
Antiporter
Freeze-fracture of membranes has provided information on the intramembranous distribution of
Proteins
A cell junction that joins one epithelial cell to ALL its immediately neighboring cells is a
Tight junction
T/F All rRNA molecules are transcribed using RNA polymerase I
True
Ends of chromosomes which shorten with each cell cycle and are thought to limit the number of cell divisions
Telomeres
Prior to mitosis, concentrations of S cyclins occurs during which of the following stages?
G1
Which of the following is not a type III intermediate filament?
Nuclear lamins
At which stage of mitosis are the chromosomes lined up on the equatorial plate
Metaphase
At which stage of mitosis do sister chromatids move to opposite poles
Anaphase
N-CAMs, ICAMs and CD4 belong to which of the following group of CAMs?
Immunoglobulin superfamily molecules
Which of the following actin-linking proteins bundle actin filaments together in microvilli?
Villin and fimbrin