Molecular Basis of Inheritance Flashcards
Transformation
A change in genotype and phenotype due to the assimilation of external DNA by a cell
Bacteriophages (phages)
Viruses that infect bacteria which gave additional evidence that DNA was the genetic material
Double Helix
The structure of a DNA molecule
Watson deduced that DNA was helical by examining an x-ray image taken by Rosalind Franklin
Anti-Parallel Strands
DNA is all built from the 5’ end to the 3’ end so strands look like a road where they go opposite ways
Base Pairing
Purines must pair with Pyrimidines due to width requirement
Purines: Adenine and Guanine
Pyrimidines: Thymine and Cytosine
Semiconservative replication
The form of DNA replication where each pair of two strands contains one “parental strand”
Origin of Replication
Origin of Replication is a site where DNA replication occurs
Template Strand
The strand that is used as a template to build another DNA strand off of
How did Alfred Hershey and Martha Chase discover that DNA was the genetic material of the cell?
They labeled a phage with 35Sulfur and 32Phosphorus, conducting an experiment in which they blend and centrifuge the mixture discovering that phosphorus was found in the pellet at the bottom.