Molecular Basis Of Genetics Flashcards
1
Q
What are the requirements of dna?
A
- has to store info
- replication mechanism
- undergoes mutation
2
Q
What’s the diameter and number of nucleotides per turn in dna?
A
Diameter- 2nm
Per turn-10 nucleotides
3
Q
What are the divisions of dna and their percentages?
A
Protein coding- 1.1 Regulatory region- 4 Introns- 44 Transponson- 45 Heterochromatin - 6.6
4
Q
What’s the purpose of transponsons?
A
Move around genome, pop in and out
… can interfere with genome and cause disease
5
Q
What’s the purpose of heterochromatin?
A
Highly condensed dna, lots of repeats, generally inactive
6
Q
What’s the genetic system that allows the colouring of calico cats?
A
In females 1 x is transcriptinally silent, … females are mosaic for all x linked alleles
7
Q
What type of mRNA regulates gene expression?
A
Mirna
Up and down regulated in cancer so contribute to problem
