Maintenence And Use Of Genetics Flashcards
What stops strands from sticking back together?
Ssb
Single something binding
What enzyme cuts dna to allow for relaxation and stop breakage?
Topoisomerase
What direction does synthesis go in?
5 to 3
What do we add to carry on synthesis when it stops half way?
Short rna primer
What degrades primers?
Exonuclease
What’s the paradox of dna replication?
Dna fragments get shorter in each replication .. we have telomeres that are added as buffers
What cells are telomeres switched off in?
Somatic cell- contributes to aging
Cri du chat is a result of what mutation?
Indel deleation
What are the 2 ways dna can be repaired?
1- direct, so remove damaged bit
2-remove a whole chunk and resynthsis
Nucleosome sliding
What are the 3 main types of gene regulation?
1-tissue specific expression
2-external signals trigger gene expression
3-regulation in time and space, ie menopause