Module Assessment 3 Flashcards
Types of Dietary Nutrient Interactions
Direct- alter absorption, metabolism, or excretion
Indirect- undesirable side effects
Phenytoin and Warfarin
low serum albumin
phenytoin- antipsychotic for seizures
warfarin- anticoagulant IV form of Coumadin
Grapefruit and cardiac meds
cytochrome c is inhibited by enzyme in grapefruit
serum drug levels may become toxic
Na and Li
alter renal absorption
high Na- Na and Li excretion
low Na- Na and Li retention
Zantac, protonix
anti gerd medications
b12, thiamin, and Fe
Antineoplastics
drug damages mucosal surfaces causing malabsorption
may damage rapidly proliferating cells-> stomatitis, esophagitis
Phenobarbital and phenytoin–>
Methotrexate—>
affects metabolism of nutrients
Phenobarbital and phenytoin–> Fe, Vit D, and K def
Methotrexate—> folate def
Lasix and K
drug increases urinary loss of nutrients
Enhances effects of ______ of drug
Theophyline and—->
MAOI’s and ——>
toxicity
Theophyline and—-> caffeine
MAOI’s and ——>tyramine
______ effects of drugs
Vit K opposes —–>
Antagonizing
Coumadin
Abx may cause
Abx and diarrhea may destroy
may cause candidiasis and
destroy intestinal bacteria
cleocin—> c, diff overgrowth
Flagyl, lunesia, biaxin may cause
may cause dysguesia
Narcotics and antipsychotics may affect
intestinal peristalsis
NSAIDs, ASA may
irritate stomach mucosa
Corticosteroids, decadron
glucose intolerance