module 8 water soluble vitamins Flashcards

1
Q

what are examples of water-soluble vitamins

A

b complex
niacin

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2
Q

what are characteristics of vitamins

A

work as coenzyme
non toxic
not stored (except B12 in liver)
excess excreted in urine

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3
Q

what is the function of thiamin

A

required as a coenzyme involved in energy production

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4
Q

what is the RDA value for thiamin

A

very small
1.1/1.2 mg/day

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5
Q

what is the thiamin deficiency called

A

beriberi

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6
Q

what are symptoms of beriberi

A

muscle weakness
neurological changes
thingling, numbness
depression

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7
Q

what does beriberi look like in the western world

A

alcoholism
1. B1 is needed as a coenzyme for enzyme involved in alcohol breakdown
2. lower absorption of B1
3. tend to have poor diet

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8
Q

what is the function of riboflavin (B2)

A

part of 2 coenzymes: FAD, FMN
involved with glucose and FA making energy (Kcal)

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9
Q

what is riboflavin deficiency

A

riboflavnosis/angular stomatis
cracking at corners of the mouth

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10
Q

what is the RDA value for riboflavin

A

1.1/1.3 mg/day

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11
Q

what is the function of niacin (nicotinic acid)

A

part of 2 coenzymes: NAD and NADP

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12
Q

what is a food source of niacin

A

corn

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13
Q

what is the niacin deficiency called

A

pellagra

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14
Q

what does pellagra do

A

weakness
dermatitis
diarrhea
dementia

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15
Q

what is 1 niacin equivelent (NE)

A

1mg niacin
= 60mg tryptophan

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16
Q

what are different forms or vitamins of B6

A

pyridoxine
pyridoxal
pyridoxamine

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17
Q

what are the B6 vitamins covered to

A

PLP
pyridoxal phosphate

18
Q

what does PLP do

A

coenzyme in reactions of protein and amino acid metabolism
formation of heme ring

19
Q

what can the conversion of tryptophan with the enzyme B6 attached turn into

A

niacin
serotonin

20
Q

what does estrogen do

A

increase activity of enzyme that converts tryptophan -> niacin

21
Q

what are symptoms of B6 deficiency

A

abnormalities in protein and AA metabolism
re: heme ring

22
Q

what are the B6 deficiencies

A

microcytic
hypo chronic
anemia
(pale tiny RBC)

23
Q

what is the RDA value for vitamin C

A

75/90 mg/day

24
Q

what is the key function of vitamin C

A

reducing agent (donate e)

25
what is vitamin C needed for
1. antioxidant 2. steroid hormone synthesis 3. reduce formation of potential carcinogens 4. required for building and maintenance of collagen 5. drug metabolism 6. enhance absorption of Fe and Ca
26
how much vitamin c if were stressed
higher glucocorticoids synthesize and excretion
27
how much vitamin c if taking an oral contraceptive
uses lower absorption of vitamin C
28
how much vitamin c for smokers
25% lower vitamin C levels
29
what are characteristics of scurvy
weakens collagen throughout the body reopening of previously closed wounds depression
30
what is the UL for ascorbic acid
2000 mg/day
31
what is ascorbic acid toxicity
osmotic diarrhea Fenton reaction
32
what is the function of Cobalamin (vit B12)
as a coenzyme in reactions that transfer methyl groups from a biomolecule to another
33
what are foods rich in B12
only in foods of animal origin
34
t or f B12 is stored well in the liver
true
35
what are signs of B12 deficiency
neurological disorder (needed to maintain myelin sheath) megaloblastic anemia
36
what is pernicious anemia
not a B12 deficiency looks clinically like megaloblastic anemia lacking intrinsic factor
37
what is the RDA value for folic acid (folate)
400 mcg/day
38
where is folate found in foods
green leafy vegetables
39
what are folate and neural tube defects (NTDS)
neural tube closure in 1st two weeks post-conception
40
what is the UL value for folate
1000