Module 6 Aliphatic Synthesis Flashcards by Emma S | Brainscape

Q

Haloalkane to nitrile

A

CN-/ethanol

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Q

Haloalkane to amine

A

NH3/ethanol

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Q

Nitrile to amine

A

H2/Ni

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Q

Nitrile to Carboxylic acid

A

H2O/HCl, heat

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Q

Hydroxynitrile to carboxylic acid

A

H2O/HCl, heat

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Q

Hydroxynitrile to amine

A

H2/Ni

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Q

Ketone to hydroxynitrile

A

NaCN (aq) / H+ (aq)

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Q

Ketone to 2º alcohol

A

NaBH4

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Q

Aldehyde to 1º alcohol

A

NaBH4

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Q

Aldehyde to hydroxynitrile

A

NaCN (aq) / H+ (aq)

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Q

Alcohol to ester

A

Carboxylic acid / conc. H2SO4

OR

Acid anhydride

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Q

Carboxylic acid to ester

A

Alcohol / conc. H2SO4

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Q

Ester to carboxylic acid

A

Dilute acid, heat

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Q

Ester to carboxylate

A

OH-, heat

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Q

Acyl chloride to ester

A

Alcohol

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Q

Acyl chloride to carboxylic acid

A

H2O

Q

Carboxylic acid to acyl chloride

A

SOCl2

Q

Acyl chloride to 1º amide

A

NH3

Q

Acyl chloride to 2º amide

A

Primary amine