Module 6 Flashcards

1
Q

CT components of skeletal muscle:

A
  • epimysium
  • perimysium
  • endomysium
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2
Q

skeletal muscles are surrounded by a fibrous

A

epimysium

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3
Q

subdivides the muscle into fascicles

A

perimysium

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4
Q

each fascicle is subdivided into muscle fibers surrounded by

A

endomysium

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5
Q

plasma membrane of skeletal muscle fibers

A

sarcolemma

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6
Q

multi nucleated; form a syncytium, are striated

A

skeletal muscle fibers

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7
Q

site where a motor neuron stimulates a muscle fiber

A

neuromuscular junction

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8
Q

varied contraction strength due to different numbers of motor units being stimulated

A

graded contractions

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9
Q

motor neuron and all the muscle fibers it innervates

A

motor unit

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10
Q

area of the muscle fiber sarcolemma where a motor neuron stimulates it using the neurotransmitter,

A

motor end plate

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11
Q

each fiber has densely packed subunits of thick and thin myofilaments called myofibrils

A

myofibrils

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12
Q

only thin filaments, primarily of the protein, actin

A

I bands

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13
Q

contain all of the thick filament with some thin filament overlap; the thick filament is the protein, myosin

A

A bands

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14
Q

are the center of the A band with no thin filament overlap

A

H bands

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15
Q

are found in the center of each I band.

A

z discs

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16
Q

The basic subunit of striated muscle contraction

A

sacromere

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17
Q

protein that runs from the Z disc to the M line and allows elastic recoil

A

titin

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18
Q

are found in the center of each A band and help hold down thick filaments

A

M lines

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19
Q

thick myofilament

A

myosin

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20
Q

thin myofilament

A

actin

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21
Q

skeletal muscle contract only when stimulated by a

A

somatic motor unit

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22
Q

axon terminal of motor neuron —- vesicles contain what type of neurotransmitter?

A

Ach

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23
Q

calcium binding site in skeletal muscle

A

troponin

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24
Q

blocks actin binding site from myosin when unactivated

A

tropomyosin

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25
troponin complex
I T C
26
inhibits binding of myosin
troponin I
27
binds to tropomyosin
troponin T
28
binds to calcium
troponin C
29
most of the calcium is stored where in the SR
terminal cisternae
30
voltage-gated calcium channels located in the transverse (T) tubules
DHP
31
calcium release channels in the sarcoplasmic reticulum
RyR
32
move Ca2+ back into SR (active transport).
SERCA (ca-atpase
33
When a second shock is applied immediately after the first, a second twitch will partially piggyback the first. This is called
summation
34
time between the stimulus and the contraction (excitation-contraction coupling to the attachment of myosin cross bridges to actin).
latent period
35
stronger contractions result in recruitment of more fibers, until all fibers are contracting.
graded contractions
36
Increasing the frequency of electrical shocks decreases the relaxation time between twitches. This is called
incomplete tetanus
37
At a certain frequency, there will be no relaxation. This is called ______a smooth, sustained contraction.
complete tetanus, `
38
Muscles are made of thin muscle cells called
intrafusal fibers
39
regular muscle fibers
extrafusal fibers
40
respond to tension a muscle puts on a tendon
golgi tendon organs
41
respond to muscle length
muscle spindle apparatus
42
two types of intrafusal fibers
nuclear bag fibers | nuclear chain fibers
43
nuclei in loose central aggregates
nuclear bag fibers
44
nuclei in rows
nuclear chain fibers
45
two types of sensory cells wrap around the fibers
- primary | - secondary
46
(annulospiral) – most stimulated at the beginning of the stretch
primary
47
(flower-spray) – respond more during sustained stretch
secondary
48
Striated and involuntary Myosin and actin filaments form sarcomeres. Contraction occurs by means of sliding thin filaments.
cardiac muscle
49
fibers are short, branched, and connected via gap junctions called
intercalated discs
50
a mass of cardiac muscle cells connected to each other via gap junctions.
myocardium
51
blood vessel walls, bronchioles, digestive organs, urinary and reproductive tracts
smooth muscle
52
2 types of cells in cardiac muscle
pacemaker and myocardial cells
53
in cardiac muscle everything is the same except what depolarizes the voltage gated DHP channel to open
sodium
54
depolarization of both DHP and RYR
calcium-induced calcium release
55
cardiac muscles can produce action potentials automatically without any innervation. how?
pacemaker
56
does not contain sarcomeres, more actin than myosin, contains gap junctions
smooth muscle
57
Also unlike the situation in skeletal muscles, action potentials can cross from one myocardial cell to another.
cardiac muscle
58
two types of smooth muscle
single unit and multi unit
59
connected via gap junction, co-ordianted contraction, gross control
single unit/visceral
60
individually innervated, independent contraction, fine control
multi-unit
61
Neurotransmitter (many different NT's)k is released along the length of an autonomic neuron from ____ (Smooth muscle)
varicosities
62
smooth muscle contraction
1. SR and ES producing Calcium 2. Ca will bind and activates calmodulin 3. Calmodulin actives MLCK 4. MLCK ---- Myosin Head 5. Cross-Bridge contraction