Module 4 Self Check-True or False/QT Prolongers

Question 1

Calcium channel blockers are generally considered safe for use during pregnancy.

Answer 1

TRUE

Question 2

Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-2 receptor blockers (ARBs) should not be used simultaneously.

Answer 2

TRUE

Question 3

Abrupt discontinuation of a beta-adrenergic blocker can cause Cardiac ischemia, exacerbations of angina pectoris and myocardial infarction (MI).

Answer 3

TRUE

Question 4

Use of a non-cardioselective beta-blocker is first line in the treatment of people who have asthma or chronic obstructive pulmonary disease.

Answer 4

FALSE

Question 5

Beta-blockers a inhibits the degradation of bradykinin and can cause a cough.

Answer 5

FALSE

Question 6

Beta-blockers are contraindicated in 2nd or 3rd-degree heart block and severe bradycardia (<45 bpm).

Answer 6

TRUE

Question 7

ARNI (Angiotensin Receptor-Neprilysin Inhibitors) are a good choice for use during pregnancy.

Answer 7

FALSE

Question 8

Hyperkalemia is a potential concern with ACE inhibitors.

Answer 8

TRUE

Question 9

ACE inhibitors, ARBs, and direct renin inhibitors have been associated with serious fetal toxicity, including renal and cardiac abnormalities and death; they are contraindicated for use during pregnancy.

Answer 9

TRUE

Question 10

The risk of rhabdomyolysis while using statins is increased in patients with renal impairment, inadequately treated hypothyroidism, and those taking other drugs associated with myopathy (e.g., colchicine).

Answer 10

TRUE

Question 11

Patients with vitamin D and coenzyme Q deficiencies are at increased risk of rhabdomyolysis while on statins.

Answer 11

TRUE

Question 12

Patients who develop muscle weakness, fatigue or pain while on statins need liver enzymes, total bilirubin, and alkaline phosphatase evaluated.

Answer 12

TRUE

Question 13

Statins target low-density lipoprotein levels.

Answer 13

TRUE

Question 14

Use of statins are contraindicated during pregnancy and lactation.

Answer 14

TRUE

Question 15

Patients on statins who develop unexplained severe muscle symptoms or fatigue should continue the statin and have monitor symptoms.

Answer 15

FALSE

Question 16

Patients on higher doses of statins have an increased risk of rhabdomyolysis.

Answer 16

TRUE

Question 17

Angiotensin receptor-neprilysin inhibitors can be combined with ACE inhibitors for better control of heart failure.

Answer 17

FALSE

Question 18

Amiodarone (Nexterone/Pacerone) carries the Black Box Warning of potential for thyroid disorders, pulmonary toxicity, hepatotoxicity, and life-threatening arrhythmias.

Answer 18

TRUE

Question 19

Ivabradine (Corlanor) is the drug of choice for heart failure in patients with a pulse under 70.

Answer 19

FALSE

Question 20

NSAIDs are a good pain medication for patients with heart failure.

Answer 20

FALSE

Question 21

Angiotensin receptor-neprilysin inhibitors can cause injury and death to the developing fetus.

Answer 21

TRUE

Question 22

Short-acting nitrates are prescribed to relieve acute symptoms.

Answer 22

TRUE

Question 23

Long-acting nitrates are for the prevention of angina.

Answer 23

TRUE

Question 24

Nitrates taken with phosphodiesterase-5 inhibitors such as sildenafil (Viagra) can cause profound hypotension.

Answer 24

TRUE

Question 25

Abrupt withdrawal of long-acting nitrates may result in vasospasm.

Answer 25

TRUE

Question 26

List the QT prolongers covered in this module

Answer 26

Amiodarone, Sotalol, Flecainide, Procainamide, Quinidine,