Module 4 L3-4 Flashcards
Vasodilation
diameter increases, fluid velocity decreases
Inflammation purpose
eliminate infection and repair damage
Local signs of acute inflammation
Heat, redness, swelling, pain, loss of function
Two major components of inflammation that contribute to acute inflammation
Vascular changes, cellular events
Vascular changes
vasodilation, increased viscosity, margination
Vasodilation
diameter increases , fluid velocity decreases
Increased viscosity
thickness from fluit loss
Vasodilation and increased viscosity lead to
margination
Margination
leukocyte sitting along inner surface of blood vessels due to slowing of blood dlow
Increased vascular permeability
transcytosis
Transycosis
Increased fluid flow through endothelial cells
Effects of vascular changes
Release transudate -small holes
Release exudate - mid holes
Results in edema
White blood cell migration
Margination, rolling, adhesion, phagocytosis
Mediates adhesion
sialyl lewis X
Opsonin
host proteins that cost microbes and target them for opsonization by lysosomal phagolysosome