Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Hematology Module 2 > module 4 CBC and INtro Anemia > Flashcards

module 4 CBC and INtro Anemia Flashcards

1
Q

Normal RBC volume

A

80-100 fL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Acanthocyte

A

spur cell. irregular thorn like spikes. no central pallor. Cholesgerol preferentially trapped in outer leaflet.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

codocytes

A

target cells. thin bell shaed increased surface area to volume.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Dacrocytes

A

teardrops. Round cell with a single elongated or pointed extremity; may be microcytic and/or hypochromic

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 166). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drepanocyte

A

Round cell with a single elongated or pointed extremity; may be microcytic and/or hypochromic

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 166). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Echinochyte

A

sea urchin. Spiculated red cells with short equally spaced projections over the entire surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

elliptocyte

A

Spiculated red cells with short equally spaced projections over the entire surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

keratocyte

A

Helmet cells. Produced when a fibrin strand impales a RBC. Red cells with one or several notches with projections that look like horns on either end

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 166). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

schistocyte

A

Fragments of red cells; variety of shapes including triangles, commas; microcytic

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 167). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

spherocyte

A

—Spherocytic red cells with dense hemoglobin content (hyperchromatic); lack an area of central pallor

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 167). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

stomatocyte

A

uniconcave red cells with the shape of a very thick cup; on stained blood smears cells have an oval or slitlike area of central pallor

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 167). Prentice Hall. Kindle Edition.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

test for echinocyte artifact

A

use plastic slides as the glass releases chemicals which can cause echinocyte formation.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Normal RBC MCH

A

30 pg.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Only hyperchromic RBC

A

Spherocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Basophillic stipling

A

bluish black inclusions of ribosomes sometimes assoiaed with mitochondria. Artifact.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cabot rings

A

Remnants of spindle fibers. Indicate dyserythropoesis.

17
Q

hOWELL jOLLEY bODIES

A

Nuclear DNA suggest nucleaer maturation abnormalities. Individual chromosome fails to attach.

18
Q

Heinz bodies

A

Denatured hemoglobin attached to band 3.

19
Q

Sideroblasts

A

erythroblasts with stainabl iron granules

20
Q

Siderocytes

A

non nucleated RBCS with stainable iron granules

21
Q

Pappenheimer bodies

A

damages lysosomes and mitchondria

22
Q

corrected reticulcute count

A

corrects for abnormally low or high hematocrit.

Patient hematocrit/ Normal hematocrit * % reticulocyte = Corrected reticulocyte count (%)

23
Q

reticuocyte count HYPOPROLIFERATIVE ANEMIAS

A

62% or an absolute reticulocyte count 675 * 10 9 /L

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 184). Prentice Hall. Kindle Edition.

24
Q

RETICULOCYTE COUNT HEMOLYTIC ANEMIA

A

corrected count 72% or an absolute count 7100 * 10 9 /L

McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 184). Prentice Hall. Kindle Edition.

25
STRESS OR SHIFT RETICULOCYTES
RELEASED EARLIER THAN NORMAL WHEN MORE RBCS NEEDED. LARGE POLYCHROMATOPHILLIC CELLS. LONGER TO MATURE.
26
RPI
The RPI is a good indicator of the adequacy of the bone marrow response in anemia. Generally speaking, an RPI 72 indicates an appropriate bone marrow response, whereas an RPI 62 indicates an inadequate compensatory bone marrow response (hypoproliferation) or an ineffective bone marrow response. McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 185). Prentice Hall. Kindle Edition.
27
RPI CALCULATION
Patient’s hematocrit/ 0.45 L/L (normal hematocrit) * Reticulocyte count (%/ ) Reticulocyte maturation time (days)
28
IMMATURE RETICULOCYTE FRACTION
BASED ON RNA CONCENTRATION IN CELL. THROUGH FLOURESCENCE AND ABSORBANCE. IRF INCREASES BEFORE RETICULOCYTE COUNT.
29
ANISOCYTOSIS ASSOCIATED WITH:
Anemias associated with an increased RDW McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 186). Prentice Hall. Kindle Edition.
30
MICROCYTOSIS ASSOCIATED WITH:
Iron-deficiency anemia; thalassemia; sideroblastic anemia, long-standing anemia of chronic disease
31
MACROCYTOSIS ASOCIATED WITH
megaloblastic anemias; hemolytic anemia with reticulocytosis; recovery from acute hemorrhage; liver disease; asplenia; aplastic anemia; myelodysplasia; endocrinopathies; alcoholism McKenzie, Shirlyn B.; Williams, Lynne. Clinical Laboratory Hematology (3rd Edition) (Pearson Clinical Laboratory Science Series) (Page 186). Prentice Hall. Kindle Edition.
32
INCREASED UNCONJUGATED BILLIRUBIN
HEMOLYSIS EITHER iv OR EV.
33
INCREASED IV HEMOLYSIS
11-9). Hemosiderin in urine (hemosiderinuria), decreased plasma haptoglobin and hemopexin (as a result of increased consumption), and increased methemalbumin
34
ERYTHROCYTE SURVIVAL STUDY
SMALL AMOUNT OF BLOOD REMOVED, RADIOLABELED. CHROMIUM IS TRAPPED. REINJECTED, AND DRAWN PERIODICALLY.
35
MASS =
PRODUCTION * SURVIVAL
36
COMPENSATION FOR HYPOXIA / ANEMIA
INCREASE IN 2-3 BPG DECREASED OXYGEN AFINITY DUE TO BOHR EFFECT
37
MCH
HB / RBC COUNT
38
MCHC
HB / HEMATOCRIT

Hematology Module 2 (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions