module 4 Flashcards

1
Q

main role of NK cells.

A

immediate innate responses, kill infected or cancer cells. (perforin and granzyme) know “self” (MHC I) or not

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2
Q

main role of basophil

A

allergic reactions and pathogens/parasites

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3
Q

main role dendritic cells

A
  • coordinate adaptive and innate (stimulate t cells)
  • APC (antigen capture and presenting)
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4
Q

main role neutrophil

A
  • first responder
  • enhance rest of immune response
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5
Q

main role monocyte

A
  • innate
  • important dfferentiate later into machrophage DC etc
  • phagocytoze pathogens
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6
Q

main role eosinophil

A
  • pathogens/ parosites
  • promtoe allergic reactions
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7
Q

T cell

A

made in bone marrow, mature in thymus.
adaptive immune repsponse.
differentiate into cytotoxic, helper, memory,

cell mediated

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8
Q

b cell

A

made in bone marrow, mature in bone marrow.
adaptive immune respose.
differentiate into memory,

make ab
apc
humoral immunity

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9
Q

differences between innate vs adaptive

A

innate- 1st, quicker, general, no memory

adaptive- slower, specific, memory

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10
Q

how do vaccines innitae memory in immune responses

A

vaccines intoruduce harmless antigens into IS which stimulate IR and AB formation. memory is created. IS able to respond to specific second exposure much quicker.

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11
Q

step by step vaccination to memory

A
  • vaccine introduce harmless antigens
  • antigens uptaken and presented (DC)
  • antigens presented, activate T cells
  • helper T see MHC II and stimuate B
  • B cells begin to differentiate into plasma b and memory b, make antibodies
  • B activate differentiation of Cytotoxic T to memory and effector
  • memory cells remain for nexttimes
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