module 4 Flashcards
main role of NK cells.
immediate innate responses, kill infected or cancer cells. (perforin and granzyme) know “self” (MHC I) or not
main role of basophil
allergic reactions and pathogens/parasites
main role dendritic cells
- coordinate adaptive and innate (stimulate t cells)
- APC (antigen capture and presenting)
main role neutrophil
- first responder
- enhance rest of immune response
main role monocyte
- innate
- important dfferentiate later into machrophage DC etc
- phagocytoze pathogens
main role eosinophil
- pathogens/ parosites
- promtoe allergic reactions
T cell
made in bone marrow, mature in thymus.
adaptive immune repsponse.
differentiate into cytotoxic, helper, memory,
cell mediated
b cell
made in bone marrow, mature in bone marrow.
adaptive immune respose.
differentiate into memory,
make ab
apc
humoral immunity
differences between innate vs adaptive
innate- 1st, quicker, general, no memory
adaptive- slower, specific, memory
how do vaccines innitae memory in immune responses
vaccines intoruduce harmless antigens into IS which stimulate IR and AB formation. memory is created. IS able to respond to specific second exposure much quicker.
step by step vaccination to memory
- vaccine introduce harmless antigens
- antigens uptaken and presented (DC)
- antigens presented, activate T cells
- helper T see MHC II and stimuate B
- B cells begin to differentiate into plasma b and memory b, make antibodies
- B activate differentiation of Cytotoxic T to memory and effector
- memory cells remain for nexttimes