Module 4 Flashcards
What are the building blocks of proteins?
Amino acids
Proteins are linear polymers of amino acids that form three-dimensional structures with specific functions.
What is the structure of an amino acid?
An amino acid consists of an a carbon connected by covalent bonds to an amino group, a carboxyl group, a hydrogen atom, and a side chain or R group.
The side chain or R group differentiates the 20 common amino acids.
How many common amino acids are there?
20
The common amino acids differ in their R groups.
How are amino acids categorized?
By the chemical properties of their R groups:
* Hydrophobic
* Hydrophilic (polar, acidic, basic)
* Special
This categorization helps in understanding the behavior of amino acids in proteins.
What type of bond links successive amino acids?
Peptide bonds
Peptide bonds connect amino acids to form proteins.
What type of reaction forms a peptide bond?
Dehydration reaction
A dehydration reaction involves the removal of a water molecule.
What does the primary structure of a protein refer to?
Amino acid sequence
This sequence determines how a protein will fold and function.
What are the two termini of a protein?
- Amino (N) terminus
- Carboxy (C) terminus
Directionality is crucial for protein structure and function.
How does the primary structure of a protein affect its other structural properties?
Determines the other three structural properties
These properties include secondary, tertiary, and quaternary structures.
What is the secondary structure of a protein primarily stabilized by?
Hydrogen bonds
Secondary structures include alpha helices and beta sheets.
What is the tertiary structure of a protein?
Three-dimensional shape of a peptide
Tertiary structure is crucial for the protein’s functionality.
What is quaternary structure in proteins?
Structure formed by two or more polypeptide subunits
This structure results in a functional protein.
What are emergent properties in quaternary proteins?
Properties not present in individual units
These properties arise from the interactions of subunits.