Module 3 - Exchange and Transport Flashcards
Why do fish and insects have specialised gas exchange system?
Multicellular, small SA:volume ratio, large diffusion distance
Can’t perform gas exchange via surface so they have gills and tracheal system
Structure of gills
Many gill filaments and lamellae = large SA
Gill lamellae have thin wall and are permeable
Countercurrent flow - water and blood pass over opposite directions, blood always passes water with high 02 concentration, maintains favourable conc gradient all across gradient
Structure of tracheal system
Spiracles, have valves to prevent water loss
Spiracles connect to trachea connect to tracheoles connect directly to respiring cells/ muscle fibres
How does gas exchange occur in tracheal system?
Rest = down concentration gradient, simple diffusion of 02 and c02, tracheal fluid containing 02 seeps in Active = ventilation, mass flow of 02 and c02, tracheal fluid containing 02 is sucked in
Function of lungs?
Site of gas exchange in mammals
What are lungs made up of?
Trachea, bronchi, bronchioles, alveoli
Structure of trachea/bronchi?
Strong c-shaped cartilage, c-shape gives flexibility
Goblet cells - make mucus, traps pathogens
Epithelial cells - have cilia, pushes mucus out of the lungs
They are the lining
Structure of bronchioles
Wall made of smooth muscle
Smooth muscle contracts, lumen smaller, bronchioles constrict, occurs near dangerous gases, reduces intake
Lining made of goblet cells and ciliated epithilial cells
Adaptation of alveoli
Many folded tiny alveoli so large SA
Thin wall so short diffusion distance
Elastic tissue so stretches increasing SA when breathing in, recoils when breathing out
Ventilation maintains concentration gradient
Adaptation of capillaries
Many tiny capillaries so large SA
One cell thick thin wall so large diffusion distance
Narrow lumen low diffusion distance
Circulation maintains concentration gradient
How 02 moves from alveoli to capillaries
Simple diffusion
How c02 moves from capillaries to alveoli
Simple diffusion
Process of breathing/ventilation
Inhalation - external intercostals contract, rib cage moves up and out, diaphragm contracts , increase thoracic cavity/ volume DECREASING pressure
Pulmonary ventilation
PV = tidal volume x breathing rate
Blood vessels of heart
Vena Cava supplies R atrium with deox blood from body
Pulmonary vein supplies L atrium with oxy blood from heart
R ventricle supplies pulmonary artery with deox blood
L ventricle supplies aorta with oxy blood
Job of valves
Ensure one way flow Atria - ventricles - arteries 2 valves - AV valves, semi-lunar valves AV valves - between atria and ventricles SL valve - between ventricles and arteries
When are AV open ore closed
Open = pressure in atria bigger than ventricles Closed = pressure in ventricles greater than atria
When are SL open or closed
Open = pressure in ventricles bigger than arteries Closed = pressure in arteries bigger than ventricles
Process of cardiac cycle
All relaxed, AV valve open SL valve closed
SA node causes atria to contract with an impulse
Sent too AV node allowing ventricles to fill with blood
Impulse travels through bundle of his and into ventricle walls through purkinje fibres causing contraction of ventricles, av valves close, sl valves open
ventricles relax, sl close, av open
Formula for cardiac output
CO = stroke volume x heart rate
CHD and myocardial infarction
High pressure damages lining of coronary artery
cholesterol build up beneath lining
breaks through lining forming atheromatous plaque
blood clot forms
blocks coronary artery
less blood flow
Risk factors of CHD
Age, gender, ethnicity
saturated fats, salts, smoking, obesity
Atheroma and aneurysm
Atheroma weakens wall of artery, blood builds up in the wall, the wall swells then bursts = aneurysm
Structure of arteries/arterioles
Narrow lumen
Thick wall
Elastic tissue - withstand pressure, recoils to maintain pressure and smooth out
Smooth muscle for vasodilation/constriction
Collagen prevents tearing
Structure of veins/venules
Wide lumen for good blood flow
Thin wall, can be squished by muscles to increase venous return
Valves prevent back flow