module 3

Question 1

Amino Acids

Answer 1

Building blocks of Proteins

Question 2

Classes of Amino Acids

Answer 2

Non - Polar Aliphatic
Aromatic
Polar, Uncharged
Polar Positively Charges
Polar, Negatively Charged

Question 3

Non Polar Aliphatic Amino Acids

Answer 3

Mainly Hydrocarbon side chains
Residues with non polar chains are often buries in the core of the protein

Question 4

Proline

Answer 4

Often found at polypeptide turns

Question 5

Glycine

Answer 5

Smallest amino acid and is the only one that is not chiral

Question 6

Methionine

Answer 6

one of 2 amino acids with sulfur group within its side chain

Question 7

Histidine

Answer 7

Can also be considered as an aromatic

Question 8

Tyrosine

Answer 8

Can be post tralation modifies through Phosphorylation

Question 9

Phosphorylation

Answer 9

Mechanism to regulate protein function

Question 10

Serine and Threonine

Answer 10

Acids with hydroxyl groups can be phosphorylates

Question 11

What causes a disulphide bond

Answer 11

two cysteines

Question 12

Disulfide bonds

Answer 12

Disulfides stabilize protein structures
Cysteine residues form these bonds
Can be inter molecular or intramolecular

Question 13

Positively Charged Amino Acids

Answer 13

+1 Charge

Question 14

Lys and Arg

Answer 14

Always carry +1 met charge at physiological pH

Question 15

Histidine

Answer 15

Imaidazole group has a pKA near physiological pH such that a fraction of cellular histidines will be +1 and the the rest will carry a net charge of 0

Question 16

Diprotic

Answer 16

Every Amino Acid has at least 2 groups that accept and donate protons

Question 17

Triprotic

Answer 17

Amino Acids ionizable groups in their side chains (KRHDECY)