Module 2.2

Question 1

THe dominant trait is always expressed

Dominant allele cannot completely mask effect of recessive allele so it blends

Non-mendelian inheritance both alleles are equally dominant

This dominance where a heterozygote has more extreme phenotype than its parents

Answer 1

Complete dominance

Incomplete dominance

co dominance

Overdominance

Question 2

Autosomal dominant diseases (4)

Answer 2

Huntington’s disease

achondroplasia (dwarfism)

polycystic kidney disease

polydactyly

Question 3

Autosomal recessive inheritance (4)

Answer 3

Cystic fibrosis

Tay-Sachs

Hemochromatosis

phenylketonuria (PKU)

Question 4

Base letter of MN blood type L comes from who (2)

Answer 4

Landsteiner
Levine

Question 5

Codominance disease/conditions (2)

Answer 5

Sickle cell anemia

ABO blood groups

Question 6

Malaria causing disease that is cancelled by sickle cell

Answer 6

Plasmodium falciparum

Question 7

Heterozygotes:

Cystic fibrosis

Thalassemia

Deafness

Answer 7

CYSTIC FIBROSIS
Cholera
Typhoid fever

THALASSEMIA
Malaria

DEAFNESS
Thicker Epidermis

Question 8

THe I antigen in the blood type

Answer 8

isoagglutinogen

Question 9

The Gene necessary to produce A and B antigens

Adds sugar frucose to substance

Answer 9

H Gene

Question 10

T or F: Whenever inbreeding occurs the proportion of rare homozygotes increases in frequency

Answer 10

True

Question 11

Group of people who would be incompatible when rossmatched with red cells of all normal ABO groups

Answer 11

Bombay

w/ h gene

Question 12

T or F: lethal alleles only cause organism to die if it is heterozygous

Answer 12

F, it will die if homozygous

Question 13

Genes that kill homozygous and heterozygous individuals

Genes that only handicap their possessor

Homozygote for allele is recessive

Answer 13

Completely lethal genes

subvital, sublethal

Recessive lethal genes

Question 14

Lethal genes in flies (say scientific name)

Answer 14

Drosophila melanogaster

Curly wings

Plum eyes and stubble bristle

Question 15

Has a gene lethal in homozygous state due to interfering with spinal development or just cause lack of tail

Answer 15

Manx cat

Question 16

Recessive Lethal gene that is due to deficiency of hexo saminidase A
Inability to break down specific membrane lipids

Destroys nerve cells in brain and spinal cord

Motor skills lost

Exaggerated startle reaction

Other intellectual and physical disability

Answer 16

Tay-Sachs disease

Question 17

Recessive Lethal gene condition that causes early death through 2 doses of a recessive allele

Answer 17

Sickle cell anemia

Question 18

Dominant lethal gene, a progressive diorder callled ___. Appear usually at 30s or 40s, affects brain’s __ which is motor control, learning, emotional.

Increased blinking, abnormal eye movements, abnormal speech

Cognitive impairments

Depression

Answer 18

Huntington’s Disease

Question 19

Conditional temperature sensitive lethal genes in flies (___) which kill larva at 30 C

Answer 19

Drosophila melanogaster

Question 20

Conditional lethal gene in humans, if they consume fava they develop anemia. G6PD allele

Answer 20

Favism

Question 21

Semi-lethal genes in humans that can impair the blood clotting, can only kill some individuals

Answer 21

Hemophilia