Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Module 2 Sympatholytics > Flashcards

Module 2 Sympatholytics Flashcards

1
Q 
Effects of Sympatholytics drugs:
A. Orthostatic Hypotension and Reflex bradycardia
B. Mydriasis
C. Tachycardia
D. All of the above
A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

These type of antagonist do not dissociate from receptors

A

Irreversible Antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Agonists that dissociate from receptors

A

Reversible Antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q 
Which of the following is/are reversible antagonist?
A. Phentolamine
B. Prazosin
C. Terazosin
D. All of the above
A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

An irreversible alpha-1 antagonist

A

Phenoxybenzamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q 
What is the adverse effect of an irreversible alpha1 antagonist?
A. Bradycardia
B. Hypertension
C. Erectile dysfunction
D. Inhibition of ejaculation
A

D (Parasympa: erection - sympa: ejaculation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

This drug is a competitive antagonist to both alpha 1 and alpha 2 receptors.

A

Phentolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What drug/s may be used for the treatment of pheochromocytoma?

A

Phenoxybenzamine / Phentolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What receptor/s is/are blocked by phenoxybenzamine?

A

Histamine (H1), ACh, and serotonin receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

This drug is higly selective for alpha-1 receptors

A

Prazosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
What is the treatment of choice for BPH? This drug has a high bioavailablity. 
A. Prazosin
B. Terazosin
C. Tamsulosin
D. Doxazosin
A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which among the alpha receptor antagonist drugs has the longest half-life?

A

Doxasozin (22-hrs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

This drug is extensively metabolized in the liver

A

Terazosin and Tamsulosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

A pt presents with HPN, headache, palpitations, and increased sweating. Furthers tests showed that the pt has a tumor in the adrenal medulla. What drug should you give for preoperative managemnt pf the disease?

A

Phenoxybenzamine - tx for pheochromocytoma (excess catechilamines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

This drug inhibits tyrosine hydroxylase. What is this drug and its side effect?

A

Metyrosine - extrapyramidal side effects (due decreased dopamine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drug is efficacious in the treatment of mild to moderate systemic HPN?

A

Prazosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q 
Which of the following is/are the effects of beta receptor antagonist drugs?
A. Positive inotropism and chronotropism
B. Negative inotropism and chronotropism
C. Increased IOP
D. Decreased VLDL
A

B. (Others kabaligtaran)

18
Q

These drugs have good oral absorption, low availability, and with rapid distribution.

A

Beta receptor antagonist drugs

19
Q

Which among the beta receptor antagonist drigs undergoes extensive hepatic metabolism?

A

Propanolol

20
Q

This drug is the prototype beta blocker

A

Propanolol

21
Q

Which among the beta receptor antagonists is similar to Doxasozin in terms of its half-life?

A

Nadolol (24hrs)

22
Q

What is/are the beta blockers that can cross the BBB?

A

Propranolol and Penbutolol

23
Q

What is the effect of beta blockers in the CVS?

A

Negative inotropism and chronotropism, increase peripheral resistance

24
Q

Which among the beta blockers are cardioselective?

A

Metoprolol, Atenolol

25
Q 
Which of the ff is the effect of beta blockers in the eye?
A. Decreased aqueous humor
B. Decreased IOP
C. Tx for glaucoma
D. All of the above
A

D

26
Q

What is the metabolic and endocrine effect of beta blockers?

A

Inhibition of lipolysis and glucogenolysis, increased VLDL and decreased HDL

27
Q

What beta blocker is the choice in COPD patients?

A

Metoprolol and atenelol

28
Q

This beta blocker is highly selective to beta-1

A

Nevibolol

29
Q

This drug has a similar action with timolol

A

Nadolol

30
Q 
Which among the beta blockers is the treatment of choice for glaucoma?
A. Nadolol
B. Timolol
C. Levobunolol
D. Betaxolol
A

B

31
Q

These drugs have partial beta agonist activity amd is used for HPN and angina

A

PAC-BOx-CP

Pindolol, Acebutolol, Carteolol, Bopindolol, Oxprenelol, Celiprolol, Penbutolol

32
Q

This drug is a potent alpha and beta blocker

A

Labetalol

33
Q

Which among the beta blockers is an ultra short acting beta 1 selective blocker?

A

Esmolol

34
Q

What is the most common adverse effect pf beta blockers?

A

Bradycardia

35
Q

What is the metabolic adverse effect of beta blockers?

A

Hypoglycemia

36
Q

Which among the beta blockers may be used for the treatment ofstage fright and alcohol withdrawal?

A

Propanolol

37
Q

Which among the beta blockers is/are effective in reducing mortality in patients with CHF?

A

Metoprolol, Bisoprolol, Carvedilol

38
Q 
Which of the following is an effect of beta blockers?
A. Reduce ventricular ectopic beats
B. Blocks adenoreceptors
C. Inhibits coversion of T4 to T3
D. All of the above
A

D

39
Q

What beta blockers are used for the treatment of glaucoma

A

Betaxolol, Carteolol, Levobunolol, Metipranolol

40
Q

TRUE or FALSE: Beta blockers increase the frequency of anginal episodes

A

False (reduce dapat)

41
Q

What other drugs is often used in conjunction with beta blockers?

A

Diuretics and vasodilators

Pharmacology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions