Module 2 Secondary Structure Flashcards

1
Q

Properties of Alpha helix

A

Amphipathic, right hand helix, -57 phi and -47 psi angle, 0.54nm per turn, 3.6 residues to form 100 degees

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2
Q

How to determine alpha helix

A
  1. Proline is not present as it breaks the helix
  2. Heptad repeat
  3. Hydrophilic and hydrophobic face
  4. Alanine, Leucine popular as hydrophobic residues
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3
Q

Properties of Beta sheets

A

Tetrahedral and planarity of molecule, 0.7nm per repeated unit, parallel and antiparallel, reverse turns

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4
Q

How to determine Beta sheets

A

Repeated sequence of alternating polar and non polar sequence

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