Module 1 Amino acids Flashcards
Name the acidic amino acids
Glutamate, Aspartate
Name the basic amino acids
Arginine, Histidine, Lysine
Non polar aliphatic R groups
Valine, Proline, Alanine, Leucine, Isoleucine, Methionine, Glycine
Aromatic groups
Phenylalanine, Tyrosine, Tryptophan
Polar uncharged R groups
Asparagine, Glutamine, Serine, Threonine, Cysteine
Glutamate Glu E
Acidic, CH2-CH2-COO sidechain, trigonal planar
Aspartate Asp D
Acidic, CH2-COO sidechain, trigonal planar
Histidine His H
Basic, CH2-(C-NH-CH=N-CH=) ring
Lysine Lys K
Basic, 4 CH2’s -NH2+
Arginine Arg R
Basic, 3CH2’s-C(NH2)=NH2+
Valine Val V
Non polar aliphatic, CH-2CH3’s
Proline Pro P
Non polar aliphatic, 3CH2’s-NH2+ ring
Leucine Leu L
Non polar aliphatic, CH2-CH-2CH3
Isoleucine LLE I
structural isomer and beta branched
Methionine Met M
2CH2-S-CH3, non polar aliphatic
Glycine Gly G
-H less steric clash, very flexible, non polar aliphatic
Alanine Ala A
-CH3, non polar aliphatic
Asparagine Asn N
polar, uncharged - CH2-C(NH2)=O
Glutamine Gln Q
polar, uncharged 2CH2 - C(NH2)=O
Serine Ser S
CH2-OH polar uncharged
Threonine Thy T
CH(CH3)(OH) polar uncharged
Cysteine Cys C
very reactive polar uncharged, CH2-SH, deprotonate at pH 7
Phenylalanine Phe F
CH2-benzene aromatic UV
Tyrosine Tyr Y
CH2-phenol aromatic UV
Tryptophan Trp W
CH2-C=CH-pentagon ring NH-hexagon (1 double bond in pentagon) (1 double bond in hexagon) aromatic UV
Which group detect proteins and act as protein probes
Aromatic
Oxidation of thiolates (SH) form
disulfide S-S bonds interchain and intrachain
