Module 11: Transplantation Immunology Flashcards
1
Q
2 purposes of MHC antigens
A
Initiate immune response
Initiate tissue rejection
2
Q
HLA antigen detection techniques
A
Serological
Molecular
3
Q
HLA antibody detection techniques
A
ELISA
Flow cytometry
4
Q
Define autograft
A
Transfer from one area to another on the same individual
5
Q
Define isograft
A
From one individual to a genetically identical individual
6
Q
Define allograft/homograft
A
Transfer between two genetically different individuals of the same species
7
Q
Define xenograft/heterograft
A
Transfer between different species
8
Q
HLA coded by MHC I genes
A
HLA A, B, C (E, F, G)
9
Q
HLA coded by MHC II genes
A
HLA D:DR, DQ, DO, DM,DP
10
Q
HLA coded by MHC III genes
A
HLA C2, C4, BF
11
Q
MHC usually identified in tissue typing
A
MHC I HLA-A, HLA-B; MHC II HLA-DR
