Module 1 jan 19

Question 1

Objective - Describe Primary, Secondary, Tertiary, quaternary protein structure - 4

Answer 1

Primary - chain of which amino acids in which order
Secondary - Folded pleated sheet or helix
Tertiary - folded 3D, +/- external causes hydrophilic/hydrophobic
Quaternary - 2 or more tertiary combined

Question 2

Objective - Describe functional & structural roles proteins play in cell, organ, organ system - 8

Answer 2

Structure - cytoskeleton - microtubules, actin filaments

Functional - Enzymes, hormones, cell receptors, cell membrane transporters, signalling

Question 3

Objective - Structure/function of ligand/voltage gated receptors - 2

Answer 3

ligand or voltage triggers (signal)

Shape of transporter changes to allow ions through

Question 4

Objective - Structure/function of G-protein coupled receptors - 2

Answer 4

Ligand activates, alpha of G-protein splits from rest, conformation change
Internally causes ATP -> cAMP or Ca++, messengers internal

Question 5

Objective - Structure/function of enzyme linked protein receptors - 2

Answer 5

Ligand links 2 receptors, they phosphorylate, this is signal

Question 6

Objective - Structure/function of lipophilic intracellular ligand - 2

Answer 6

Ligand goes through cell membrane, binds to hormone receptor

Attaches to DNA to affect gene expression

Question 7

Objective - Relate DNA replication, transcription, translation to protein production - 6

Answer 7

Helicase - separates DNA strands
DNA Polymerase - build new DNA strand
RNA Polymerase - build new RNA strand
Codon - 3 nucleotides, code for 1 amino acid
tRNA - Anti-codon to Amino acid translator
Ribosome - mRNA + tRNA creates amino acid chain