Mod 5 Chap 33 Flashcards
used in the treatment, palliation, diagnosis, cure, and prevention of disease
Drug therapy is used for?
?? is affected by the drugs chemical and physical properties and the patients physical status; a greater percentage of body fat results in slower drug ?? the less a pt wigs, the more concentrated the drug is and the more powerful its effect.
Distribution of a drug is affected by?
what causes an increase in unbound drug in circulation; this causes increased drug activity and possible toxicity. Eldery often have decreased levels.
Decreased albumin causes?
most drugs are ? in the liver and excreted by the kidneys
Metabolized
is the intended effect
Primary effect
may be desirable or undesirable, often the side effects of the drug
secondary effect
is the range of levels of the drug in the blood that will produce the desired effect without causing toxic effects
therapeutic range
stimulation or depression,
replacement,
inhibition or killing,
irritation.
four types of action
alcohol has a ? effect when combined with drugs that depress the CNS
synergistic effect
foods can affect the ? or ? of drugs
absorption; action
what must be followed when administering drugs?
The six rights
when giving medications to children the does is based on ? and ?
age; weight
? can be related to lack of info, financial problems, health beliefs, unpleasant side effects, or cognitive issues
Noncompliance
n.urses are held legally responsible for the ? and ? effects of drugs
safe and therapeutic effects of the drugs
1) be able to locate the information about each drug
2) consistently calculate drug dosages accurately,
3) devise a method for consistently using the six rights of medication administration
4) recognize the nursing implications for each drug administered
to be able to prepare for medication administration you need to know these 4 things
points you need to remember about the druge or teach to the patient.
nursing implications
name not protected by trade mark (ibuprofen)
generic name
name protected by a trademark (may have many different names) (advil motron ect.)
trade name
describes the chemical composition of the drug
chemical name
to administer and individual dose of a medication at a specified time.
Nurses role in drug therapy
what determines the route of administration
form of a drug
? of a particular form is designed to enhance its absorption and metabolism in the body?
composition
further regulates dispensing and handling of all controlled substances. it classifies drugs according to their medical usefulness and their potential for abuse.
The comprehensive drug abuse prevention and control acts of 1970
for a drug to pass U.S. Food and Drug Administration (FDA) approval and be marketed it must meet 5 standards in what areas?
1) purity
2) potency
3) bioavailability
4) efficacy
5) safety
what med stimulates heart muscle fibers to contract more powerfully and its effect on the hearts electrical properties causes changes in rate and rhythm
Digoxin
what med depresses the function of cell groups in the central nervous system, causing drowsiness.
barbiturates
what med has the ability to block cell division
antineoplastic drugs such as vincristine
study of how drugs enter the body and reach their site of action and how they are metabolized and excreted?
pharmacokinetics
The rate of absorption is determined by many factors including? (8)
1) body weight
2) age
3) sex
4) disease conditions
5) genetic factors
6) immune mechanisms
7) physiologic and emotional factors
8) hot and cold weather
types and concentrations of substances other than the drug that can be in the tablet, capsule suspension ect.
purity
amount of active drug in the preparation contributing to its strength
potency
drugs ability to dissolve, be absorbed, and be transported in the body to its desired site of action
bioavailability
laboratory studies providing proof that the drug is effective for its intended use
efficacy
sufficient studies completed to indicate potential side effects, adverse effects, and toxic reactions; safety is determined from the data
safety
drugs with no accepted medical use, a high potential for abuse, and lacking accepted safety measures. (opiods, psychedelics, cannabis derivatives, methaqualone, phencyclidine) ex: heroin, lysergic acid diethylamide (LSD), phenosulfonphthalein (PSP) and peyote
schedule I drugs
drugs with a medical use, a high potential for abuse, with severe psychological or physical dependence (opioids, psychostimulants, barbiturates and cannabinoids) ex: amobarbital (tuinal) amphetamine, meperidine, morphine, and methadone
schedule II drugs